Table 2. Multivariable regression for factors associated with telomere length- NHANES 1999–2002.
| Model 1 unadjusted | Model 2 adjusted a | |||||
|---|---|---|---|---|---|---|
| β | 95%CI | p-value | β | 95%CI | p-value | |
| Age | -0.0146 | -0.0162, -0.0130 | <0.001 | -0.0142 | -0.0157, -0.0127 | <0.001 |
| Gender (Reference = Male) | ||||||
| Female | 0.0252 | -0.0265, 0.0769 | 0.328 | 0.0460 | -0.0015, 0.0934 | 0.0569 |
| Race/Ethnicity (Reference = NH White) | ||||||
| Hispanic | 0.0681 | -0.0692, 0.2054 | 0.319 | -0.0053 | -0.137, 0.1264 | 0.9352 |
| NH Black | 0.1687 | 0.0802, 0.2572 | <0.001 | 0.1186 | 0.028, 0.2092 | 0.0121 |
| Other | 0.0396 | -0.1005, 0.1797 | 0.568 | -0.0141 | -0.1502, 0.122 | 0.8334 |
| Educational Status (Reference = High School) | ||||||
| <12th Grade | -0.1203 | -0.1825, -0.0581 | <0.001 | -0.0679 | -0.1365, 0.0006 | 0.052 |
| College Graduate | -0.0023 | -0.0689, 0.0642 | 0.943 | 0.0305 | -0.0357, 0.0967 | 0.354 |
| Marital Status (Reference = Married/with Partner) | ||||||
| Divorced/Widowed/Separated | -0.1111 | -0.1655, -0.0566 | <0.001 | -0.0128 | -0.0722, 0.0465 | 0.6614 |
| Never Married | 0.3162 | 0.2422, 0.3901 | <0.001 | 0.0979 | 0.0233, 0.1726 | 0.0119 |
| Family PIR | -0.0127 | -0.0354, 0.0100 | 0.261 | -0.0048 | -0.0275, 0.018 | 0.6699 |
| Physical Activity (Reference = Physically Active) | ||||||
| Physically Inactive | -0.1158 | -0.1653, -0.0663 | <0.001 | -0.0151 | -0.0537, 0.0236 | 0.4316 |
| Biomarkers of allostatic load | ||||||
| Systolic blood pressure | -0.0030 | -0.0044, -0.0015 | <0.001 | 0.0011 | -0.0001, 0.0023 | 0.0631 |
| Diastolic blood pressure | 0.0041 | 0.0022, 0.0060 | <0.001 | 0.0001 | -0.0018, 0.0018 | 0.9755 |
| Heart rate | -0.0008 | -0.0026, 0.0009 | 0.325 | -0.0021 | -0.0036, -0.0006 | 0.0074 |
| Total cholesterol | -0.0002 | -0.0007, 0.0004 | 0.516 | -0.0001 | -0.0007, 0.0004 | 0.5865 |
| High-density lipoprotein cholesterol | 0.0027 | 0.0009, 0.0044 | 0.004 | 0.0023 | 0.0005, 0.0041 | 0.0134 |
| BMI (kg/m2) | -0.0093 | -0.0133, -0.0052 | <0.001 | -0.0068 | -0.0105, -0.0031 | 0.0007 |
| Glycosylated hemoglobin | -0.0370 | -0.0573, -0.0167 | <0.001 | -0.0004 | -0.0257, 0.0249 | 0.9751 |
| C-reactive protein | -0.0538 | -0.0993, -0.0083 | 0.022 | -0.0558 | -0.0903, -0.0214 | 0.0025 |
| Albumin | 0.1664 | -0.3897, 0.7225 | 0.545 | 0.2317 | -0.6846, 1.1481 | 0.609 |
| Allostatic load (Reference = Low) | ||||||
| High | -0.1735 | -0.2226, -0.1244 | <0.001 | -0.0697 | -0.1166, -0.0228 | 0.005 |
| Charleston Comorbidity Index | -0.0723 | -0.0823, -0.0624 | <0.001 | -0.0044 | -0.0173, 0.0086 | 0.4971 |
DV: Telomere length in kbp
a Adjusted for age, gender, race/ethnicity, education, PIR, and physical activity. Abbreviations: BMI: body mass index, CI: confidence interval, NH: Non-Hispanic, PIR: poverty income ratio. p-value less than 0.05 are bold.