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. 2019 Aug 20;13(8):e0007144. doi: 10.1371/journal.pntd.0007144

Table 9. Definition of severe dengue fever (SDF) in the new World Health Organization (WHO) classification and two proposed revisions.

Original criteria for diagnosing severe dengue fever 1st proposed revision 2nd proposed revision
Patients with any of the following features: Patients with any of the following features: Patients with any of the following features:
A- Severe plasma leakage leading to:
1- Shock or
2- Fluid accumulation leading to respiratory distress
A- Severe plasma leakage leading to:
1- Shock or
2- Fluid accumulation leading to respiratory distress
A- Severe plasma leakage leading to:
1- Shock or
2- Fluid accumulation leading to respiratory distress
B- Severe bleeding as evaluated by clinician B- Severe bleeding as evaluated by clinician B- Severe bleeding as evaluated by clinician
C- Severe organ involvement:
    • Liver: AsT or AlT > = 1000 IU/L
    • CNS: impaired consciousness
    • Heart and other organs
C- Severe organ involvement:
    • Liver: AsT or AlT > = 1000 IU/L
    • CNS: impaired consciousness
    • Heart and other organs
C- Severe organ involvement:
    • Liver: AsT or AlT > = 1000 IU/L
    • CNS: impaired consciousness
    • Heart and other organs
D- Acute decompensation of chronic disease D- Acute decompensation of chronic disease
E- Minor bleeding with thrombocytopenia <20,000 platelets/mm3