Table 2. Experimental Data for Analogs of Compounds 1 and 3.

^aK_i value expressed as the mean ± SEM from three independent experiments performed in duplicate or triplicate.

^bIC₅₀ value expressed as the mean ± SEM from three independent experiments performed in duplicate or triplicate. Inactive compounds (>10 000 nM) were tested in one experiment performed in triplicate.