Table 2.
Multivariable covariate-adjusted Cox models for colorectal cancer-specific survival
| Patient characteristics | Colorectal cancer–specific HRa (95% CI)b | Colorectal cancer–specific P valuec |
|---|---|---|
| Prior cancer diagnosis (vs none) | ||
| Prior non-leukemic malignancies | .930 (.909 to .952) | <.001 |
| Prior leukemias | 1.263 (1.116 to 1.430) | <.001 |
| Age (vs 20–65), y | ||
| < 20 | .931 (.748 to 1.158) | .531 |
| > 65 | 1.376 (1.361 to 1.392) | <.001 |
| Sex (vs female) | ||
| Male | 1.124 (1.112 to 1.136) | <.001 |
| Race (vs white) | ||
| Black | 1.135 (1.116 to 1.154) | <.001 |
| Others | .872 (.854 to .890) | <.001 |
| Marital status (vs single) | ||
| Married | .895 (.880 to .910) | <.001 |
| Separated | 1.116 (1.066 to 1.168) | <.001 |
| Divorced | .942 (.920 to .965) | <.001 |
| Widowed | 1.108 (1.087 to 1.129) | <.001 |
| Stage (VS Localized) | ||
| Regional | 2.983 (2.937 to 3.029) | <.001 |
| Distant | 13.548 (13.331 to 13.769) | <.001 |
| Grade (Vs Well Differentiated) | ||
| Moderately Differentiated | 1.153 (1.132 to 1.174) | <.001 |
| Poorly Differentiated | 1.668 (1.634 to 1.701) | <.001 |
| Undifferentiated and Anaplastic | 1.904 (1.828 to 1.983) | <.001 |
| Radiation (Vs No) | ||
| Yes | 1.019 (1.004 to 1.034) | .011 |
| Surgery (Vs No) | ||
| Yes | .434 (.427 to .442) | <.001 |
| Ablation | 1.058 (.918 to 1.219) | .435 |
athis number represent the hazard ratio for all cause and colorectal cancer specific death for the above coverables. All statistical tests were tow-sided
bthis represents confidence interval
cTwo-sided P value was calculated from multivariable covariate-adjusted Cox models