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. 2019 Aug 29;7:233. doi: 10.1186/s40425-019-0703-0

Table 1.

Intratumoral PD-L2 expression and TILs in relation to clinicopathologic characteristics of PDAC

Intratumoral expression
PD-L2 CD3 CD8 FOXP3
N Low (0–1) High (2–3) P Low High P Low High P Low High P
Sex
 Male 158 125 33 0.540 113 45 0.805 129 29 0.066 131 27 0.502
 Female 147 112 35 107 40 131 16 126 21
Age
< 60 106 86 20 0.340 76 30 0.138 86 20 0.139 88 18 0.663
≥60 199 152 47 144 55 174 25 169 30
Location
 Head 181 136 45 0.348 130 51 0.913 153 28 0.885 147 34 0.030
 Body 62 49 13 44 18 53 9 59 3
 Tail 62 52 10 46 16 54 8 51 11
Grade
 Well 16 14 2 0.361 10 6 0.677 14 2 0.908 13 3 0.941
 Moderate 175 140 35 127 48 150 25 148 27
 Low 114 85 29 83 31 96 18 96 18
Tumor stage
 T1 51 43 8 0.494 33 18 0.252 40 11 0.212 45 6 0.694
 T2 176 135 41 133 43 149 27 147 29
 T3 78 60 18 54 24 70 8 65 13
Node stage
 N0 154 125 29 0.020 109 45 0.343 137 17 0.007 133 21 0.562
 N1 108 79 29 76 32 83 25 88 20
 N2 43 40 3 35 8 35 8 36 7
AJCC stage
 I 124 103 21 0.154 90 34 0.274 109 15 0.071 108 16 0.509
 II 138 101 37 95 43 111 27 113 25
 III 43 34 9 35 8 40 3 36 7

TILs tumor infiltrating lymphocytes, PDAC pancreatic ductal adenocarcinoma