Table 1.
Intratumoral expression | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PD-L2 | CD3 | CD8 | FOXP3 | ||||||||||
N | Low (0–1) | High (2–3) | P | Low | High | P | Low | High | P | Low | High | P | |
Sex | |||||||||||||
Male | 158 | 125 | 33 | 0.540 | 113 | 45 | 0.805 | 129 | 29 | 0.066 | 131 | 27 | 0.502 |
Female | 147 | 112 | 35 | 107 | 40 | 131 | 16 | 126 | 21 | ||||
Age | |||||||||||||
< 60 | 106 | 86 | 20 | 0.340 | 76 | 30 | 0.138 | 86 | 20 | 0.139 | 88 | 18 | 0.663 |
≥60 | 199 | 152 | 47 | 144 | 55 | 174 | 25 | 169 | 30 | ||||
Location | |||||||||||||
Head | 181 | 136 | 45 | 0.348 | 130 | 51 | 0.913 | 153 | 28 | 0.885 | 147 | 34 | 0.030 |
Body | 62 | 49 | 13 | 44 | 18 | 53 | 9 | 59 | 3 | ||||
Tail | 62 | 52 | 10 | 46 | 16 | 54 | 8 | 51 | 11 | ||||
Grade | |||||||||||||
Well | 16 | 14 | 2 | 0.361 | 10 | 6 | 0.677 | 14 | 2 | 0.908 | 13 | 3 | 0.941 |
Moderate | 175 | 140 | 35 | 127 | 48 | 150 | 25 | 148 | 27 | ||||
Low | 114 | 85 | 29 | 83 | 31 | 96 | 18 | 96 | 18 | ||||
Tumor stage | |||||||||||||
T1 | 51 | 43 | 8 | 0.494 | 33 | 18 | 0.252 | 40 | 11 | 0.212 | 45 | 6 | 0.694 |
T2 | 176 | 135 | 41 | 133 | 43 | 149 | 27 | 147 | 29 | ||||
T3 | 78 | 60 | 18 | 54 | 24 | 70 | 8 | 65 | 13 | ||||
Node stage | |||||||||||||
N0 | 154 | 125 | 29 | 0.020 | 109 | 45 | 0.343 | 137 | 17 | 0.007 | 133 | 21 | 0.562 |
N1 | 108 | 79 | 29 | 76 | 32 | 83 | 25 | 88 | 20 | ||||
N2 | 43 | 40 | 3 | 35 | 8 | 35 | 8 | 36 | 7 | ||||
AJCC stage | |||||||||||||
I | 124 | 103 | 21 | 0.154 | 90 | 34 | 0.274 | 109 | 15 | 0.071 | 108 | 16 | 0.509 |
II | 138 | 101 | 37 | 95 | 43 | 111 | 27 | 113 | 25 | ||||
III | 43 | 34 | 9 | 35 | 8 | 40 | 3 | 36 | 7 |
TILs tumor infiltrating lymphocytes, PDAC pancreatic ductal adenocarcinoma