Table 1.
Baseline characteristics
| Characteristic | Total | Men | Women | p value |
|---|---|---|---|---|
| Participants, n (%) | 1030 | 679 (66) | 351 (34) | < 0.001 |
| Age, years | 65 (10) | 65 (10) | 64 (11) | 0.81 |
| Current smoker, (%) | 151 (15) | 105 (16) | 46 (13) | 0.31 |
| Diabetes duration, years | 11 [6, 17] | 12 [6, 17] | 10 [5, 17] | 0.19 |
| Ischemic heart disease, n (%) | 192 (19) | 161 (24) | 31 (8) | < 0.001 |
| Systolic blood pressure (mmHg) | 136 (17) | 134 (18) | 138 (17) | 0.001 |
| Body Mass Index (kg/m2) | 30.3 (5.7) | 30.1 (5.1) | 30.6 (6.6) | 0.16 |
| Cholesterol (mmol/l) | 4.1 [3.5; 4.8] | 4.0 [3.4; 4.6] | 4.4 [3.8; 5.1] | < 0.001 |
| LDL (mmol/l) | 2.0 [1.2; 1.8] | 1.9 [1.5; 2.5] | 2.1 [1.6; 2.8] | 0.001 |
| HDL (mmol/l) | 1.2 [1.0; 1.4] | 1.1 [0.9; 1.3] | 1.3 [1.1; 1.6] | < 0.001 |
| Triglyceride (mmol/l) | 1.8 [1.2; 2.5] | 1.8 [1.2; 2.6] | 1.6 [1.2; 2.3] | 0.032 |
| HbA1C (mmol/mol) | 55 [48; 66] | 55 [48; 65] | 54 [46; 66] | 0.69 |
| P-creatinine (µmol/l) | 79 [66; 98] | 84 [73; 104] | 67 [56; 83] | < 0.001 |
| CAT (mm) | 11.9 (3.6) | 12.1 (3.7) | 11.4 (3.5) | 0.004 |
| EAT (mm) | 5.0 (1.8) | 5.0 (1.8) | 5.0 (1.9) | 0.86 |
| PAT (mm) | 6.9 (2.8) | 7.1 (2.8) | 6.4 (2.6) | < 0.001 |
| Composite end-point, n (%) | 248 (24) | 191 (28) | 57 (16) | < 0.001 |
Data is expressed as means (SD), medians (IQR) and number (n) and percentage (%). Pooled 2-sample t-tests was used for parametric means (SD) or Mann–Whitney U tests for non-parametric data (median (IQR) values). Chi2 test was used for categorical data
EAT epicardial adipose tissue, HbA1c glycated hemoglobin, HDL high-density lipoprotein, LDL low-density lipoprotein, PAT pericardial adipose tissue, CAT total cardiac adipose tissue