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. 2019 Aug 30;18:114. doi: 10.1186/s12933-019-0917-y

Table 2.

Association of high levels of cardiac fat (> median) with CVD and all-cause mortality

Adipose tissue Model Composite (n = 248) Men Women
Composite (n = 191) Composite (n = 57)
HR (95% CI) p value HR (95% CI) p value HR (95% CI) p value
High EAT 1 1.46 (1.13; 1.88) 0.004 1.54 (1.15; 2.10) 0.004 1.22 (0.72; 2.06) 0.46
2 1.31 (1.01; 1.69) 0.038 1.40 (1.05; 1.87) 0.024 1.08 (0.63; 1.83) 0.79
3 1.32 (0.99; 1.78) 0.057 1.41 (1.01; 1.96) 0.041 1.16 (0.62; 2.17) 0.65
High PAT 1 1.07 (0.83; 1.37) 0.62 0.95 (0.72; 1.27) 0.46 1.22 (0.72; 2.07) 0.46
2 0.90 (0.70; 1.16) 0.42 0.83 (0.63; 1.10) 0.21 1.15 (0.67; 1.95) 0.62
3 0.84 (0.63; 1.12) 0.23 0.79 (0.57; 1.09) 0.16 1.05 (0.56; 1.97) 0.87
High CAT 1 1.20 (0.93; 1.54) 0.16 1.14 (0.86; 1.52) 0.43 1.24 (0.73; 2.10) 0.43
2 1.02 (0.79; 1.31) 0.88 1.00 (0.75; 1.33) 0.99 1.10 (0.64; 1.87) 0.73
3 0.97 (0.72; 1.30) 0.82 0.97 (0.69; 1.35) 0.86 1.04 (0.55; 1.98) 0.62

HR values are presented according to high (> median) vs. low (< median) levels of adipose tissue

Model 1 is unadjusted

Model 2 is adjusted for age, sex

Model 3 is adjusted for age, sex, LDL, diabetes duration, HbA1c, systolic blood pressure, smoking and BMI

CI confidence interval, EAT epicardial adipose tissue, HR hazard ratio, PAT pericardial adipose tissue, CAT total cardiac adipose tissue