Table 3.
Performance of adipose tissue in predicting the composite end-point
| All patients | C-statistics | Net reclassification index | ||
|---|---|---|---|---|
| Model 1 (95% CI) | Model 3 (95% CI) | Model without vs. with adipose tissue | ||
| Percent (95% CI) | p value | |||
| Model without adipose tissue | 0.67 (0.63–0.72) | |||
| Model including | ||||
| EAT | 0.53 (0.49–0.58) | 0.68 (0.63–0.72) | 19.6% (1.4–37.8) | 0.035 |
| High EAT | 0.54 (0.50–0.58) | 0.67 (0.63–0.72) | 20.8% (2.5–39.1) | 0.026 |
| Men | ||||
| Model without adipose tissue | 0.65 (0.60–0.70) | |||
| Model including | ||||
| EAT | 0.54 (0.49–0.59) | 0.66 (0.61–0.70) | 17.7% (− 3.1 to 38.5) | 0.09 |
| High EAT | 0.55 (0.50–0.59) | 0.65 (0.60–0.70) | 19.6% (1.1–40.0) | 0.06 |
| Women | ||||
| Model without adipose tissue | 0.66 (0.55–0.76) | |||
| Model including | ||||
| EAT | 0.50 (0.39–0.60) | 0.66 (0.56–0.77) | − 4.3% (− 42.8 to 34.1) | 0.83 |
| High EAT | 0.52 (0.43–0.60) | 0.66 (0.55–0.77) | 20.3% (20.6–61.2) | 0.33 |
Adipose tissue variables are presented as continuous or as binary variables: high (> median) vs. low (< median) levels of adipose tissue
Model 1 is unadjusted
Model 3 is adjusted for age, sex, LDL, diabetes duration, HbA1C, systolic blood pressure, smoking and BMI
CI confidence interval, EAT epicardial adipose tissue, HR hazard ratio, PAT pericardial adipose tissue, CAT total cardiac adipose tissue