Fig. 9.

ipRGCs light responses across development. a Representative light response traces from M1, M2, and M4 cells at P6, P8, P10, P14, and Adult timepoints. Blue rectangle indicates start and end of light stimulus. Black dotted line indicates − 65 mV. b, c M1 ipRGC maximum light response (b) and light onset (c). d, e M2 ipRGC maximum light response (d) and light onset (e). f, g M4 ipRGC maximum light response (f) and light onset (g). Light onset was defined by time to reach 50% of maximum depolarization. Graphs are Mean ± SD, n = 5–14 per subtype/age, *p < 0.05, **p < 0.01 when compared to Adult time point