Table 1.

Liver norepinephrine following 6-OHDA or phenol-based hepatic denervation

Relative to respective vehicle	Normal Chow Vehicle	Normal Chow 6-OHDA	High Fat Diet Vehicle	High Fat Diet 6-OHDA
Liver	1.00 ± 0.11	0.23 ± 0.10*	1.00 ± 0.23	0.15 ± 0.03*
Absolute values	Normal Chow Vehicle	Normal Chow 6-OHDA	High Fat Diet Vehicle	High Fat Diet 6-OHDA
	5.21 ± 0.72	1.21 ± 0.55*	4.23 ± 0.97	0.64 ± 0.12*
Relative to respective sham	Normal Chow Sham	Normal Chow Denervation	High Fat Diet Sham	High Fat Diet Denervation
Liver	1.00 ± 0.22	0.44 ± 0.12*	1.00 ± 0.25	0.33 ± 0.11*
Spleen	1.00 ± 0.13	0.99 ± 0.13	1.00 ± 0.06	0.92 ± 0.11
Kidney	1.00 ± 0.03	0.90 ± 0.06	1.00 ± 0.05	1.01 ± 0.03
Pancreas	1.00 ± 0.15	0.75 ± 0.12	1.00 ± 0.07	0.88 ± 0.09
Absolute values	Normal Chow Sham	Normal Chow Denervation	High Fat Diet Sham	High Fat Diet Denervation
Liver	1.50 ± 0.44	0.66 ± 0.13*	2.09 ± 1.56	1.18 ± 0.57
Spleen	11.21 ± 2.06	13.94 ± 2.74	14.28 ± 4.92	22.73 ± 7.33
Kidney	14.31 ± 2.36	13.85 ± 2.94	10.00 ± 3.53	17.21 ± 5.00
Pancreas	10.03 ± 2.61	8.25 ± 2.44	10.36 ± 4.41	18.63 ± 6.69

Tissue norepinephrine measurements [absolute values (ng/mg protein) or relative to respective control group] three days following vehicle or 6-OHDA, as well as one week following sham or phenol-based hepatic denervation.

^*p<0.05 vs. control within each diet group.