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. Author manuscript; available in PMC: 2020 Oct 8.
Published in final edited form as: Biochem Biophys Res Commun. 2019 Aug 14;518(1):178–182. doi: 10.1016/j.bbrc.2019.08.027

Figure 2.

Figure 2.

1918 NS1-ED exists as a monomer in solution. (A) Crystal structure of 1918 NS1-ED W187A (PDB ID: 6DGK). The α3-α3 dimeric interface is shown in blue. For comparison, NMR structure of 1918 NS1-ED W187R (shown in green) is superimposed to chain A of the crystal structure. (B) The NMR R2 / R1 ratio as a function of primary structure of 1918 NS1-ED. The experimental and HYDRONMR-calculated values of conformationally rigid residues are shown in black and red circles, respectively.