Table 2.
Percentages of immunopositive cells1 for Ibal and LCMV in mice with LCMV clone 13 infection, with and without EtOH exposure.
| Brain Region | Protein | EtOH−/LCMV+ (n = 5–6)3 |
EtOH+/LCMV+ (n = 4) |
p-value2 |
|---|---|---|---|---|
| Frontal cortex | Iba-1 | 5.3 (2.7) | 5.6 (2.8) | 0.89 |
| LCMV NP | 6.7 (1.7) | 3.5 (1.2) | 0.01 | |
| Hippocampus | Iba-1 | 4.4 (1.6) | 3.2 (3.3) | 0.48 |
| LCMV NP | 6.5 (3.4) | 4.5 (2.7) | 0.39 | |
| Cerebellum | Iba-1 | 4.0 (1.1) | 4.6 (2.0) | 0.55 |
| LCMV NP | 7.3 (3.5) | 6.2 (3.3) | 0.57 |
Cell counts were normalized by the area analyzed, and the data shown are the percentages of immunopositive cells within each brain region of interest (SD).
p-values from t-tests are reported.
Immunostaining of the hippocampus from the EtOH-/LCMV+ group was quantifiable in five of six animals.