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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: J Physiol. 2019 Jul 27;597(17):4503–4519. doi: 10.1113/JP278338

Figure 6. Effect of donor age and pharmacology on red blood cell intracellular ATP in normoxia and hypoxia.

Figure 6.

RBC intracellular ATP increased significantly during hypoxia in all age groups and drug conditions. A: intracellular ATP was significantly lower in older (n = 10) compared to young (n = 9) adults during hypoxia with Y-27632, although the mean change from normoxia to hypoxia was unaffected by age. B: diamide significantly decreased intracellular ATP vs. saline during normoxia and hypoxia in young (n = 11) and older (n = 10) adults. C: intracellular ATP in young (n = 10) and older (n = 12) adults was unaffected by age group or drug condition. *P < 0.05 vs. control (within age); ‡P < 0.05 vs. normoxia (within condition)