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. Author manuscript; available in PMC: 2020 Sep 1.

Published in final edited form as: J Physiol. 2019 Jul 27;597(17):4503–4519. doi: 10.1113/JP278338

Table 1.

Subject characteristics

	Study 1						Study 2
	Deformability		Y-27632		Diamide		cAMP and ATP
	Young	Older	Young	Older	Young	Older	Young	Older
Male:Female	6:3	4:5	7:6	6:8	8:5	4:6	7:7	8:5

Age (years)	24±1	64±2^†	22±1	65±2^†	23±1	65±3^†	25±1	65±2^†

Body mass index (kg/m²)	22.7±0.8	25.6±1.1	23.0±0.8	24.9±0.7^†	23.2±0.8	25.1±0.9	22.4±0.6	25.2±0.8^†

Body fat (%)	24.3±2.2	34.2±3.0^†	24.7±1.8	34.9±2.1^†	25.6±2.4	34.0±2.9^†	23.7±1.9	31.3±2.0^†

Total cholesterol (mg/dL)	158±12	193±9^†	159±9	191±9^†	161±9	195±11^†	156±6	197±10^†

LDL cholesterol (mg/dL)	94±10	115±7	94±7	117±7^†	97±7	118±10	80±6	115±8^†

HDL cholesterol (mg/dL)	49±3	58±6	50±3	54±5	50±3	60±6	60±3	60±4

LDL:HDL	2.0±0.2	2.2±0.3	1.9±0.2	2.5±0.3	2.0±0.2	2.1±0.3	1.4±0.1	2.0±0.2^†

Triglycerides (mg/dL)	80±8	103±19	75±12	100±11	77±10	87±9	80±6	107±9^†

^†

P < 0.05 vs. young (within condition)