Table 1.

Patient characteristics

Patient no.	Dose cohort (mg)	Tumor histology	Race	Sex	Age (y)	BSA(m2)	Prior therapy
1	5.5	Prostate	White	M	92	1.8	N/A
2		Prostate	African American	M	76	2.2	RT
3		Prostate	White	M	79	2	RT and ADT
4	11	Prostate	White	M	75	2.3	ADT
5		Prostate	African American	M	71	-	N/A
6		Prostate	White	M	82	1.9	N/A
7	16.5	Prostate	White	M	68	-	N/A
8		Prostate	White	M	68	1.7	RT
9		Prostate	White	M	65	1.7	RT and ADT
10	33	Prostate	White	M	91	1.8	N/A
11		Multiple myeloma	White	M	57	2.4	RT, RVD, and CT
12		MPNST	Asian	M	37	1.8	RT and CT
13		NSCLC	White	M	67	1.9	RT and CT
14		Multiple myeloma	White	F	37	1.6	RVD
15	49.5	NSCLC	African American	F	56	1.7	RT and CT

Abbreviations: ADT = androgen deprivation therapy, BSA = body surface area calculated with Du Bois formula, CT = chemotherapy, MPNST = malignant peripheral nerve sheath tumor, NSCLC = non-small cell lung cancer, RT = radiation therapy, RVD = lenalidomide, bortezomib, and dexamethasone.