Table 6.
Average pain reduction
| Average change in numerical value from baseline |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Dose cohort (mg) | Total (N = 15) | Assessment timepoint | Worst pain last 24 h mean ± SD | Least pain last 24 h mean ± SD | Average pain mean ± SD | Pain right now mean ± SD | ||||
| 5.5 mg | 3 | End of RT | −4 | ± 1.4 | −1.5 | ± 2.1 | −2.5 | ± 0.7 | −2 | ± 0 |
| First follow-up | −2.5 | ± 0.7 | −1.5 | ± 1.4 | −1.5 | ± 0.7 | −2 | ± 0 | ||
| 11 mg | 3 | End of RT | −1.7 | ± 1.5 | −2.7 | ± 3.8 | −2.3 | ± 4.0 | 1.7 | ± 2.9 |
| First follow-up | −0.7 | ± 5.0 | −1.3 | ± 4.9 | −0.7 | ± 4.6 | 1.7 | ± 1.2 | ||
| 16.5 mg | 3 | End of RT | −1 | ± 1.4 | −1 | ± 2.8 | −1.5 | ± 3.5 | −0.5 | ± 2.1 |
| First follow-up | −0.7 | ± 0.6 | −2.3 | ± 2.1 | −2 | ± 2 | −2.7 | ± 3.8 | ||
| 33 mg | 5 | End of RT | −1 | ± 2 | −0.2 | ± 0.5 | −1.2 | ± 1.3 | −0.6 | ± 1.1 |
| First follow-up | −2 | ± 2 | 0 | ± 1 | −1 | ± 1 | −0.8 | ± 1.3 | ||
| 49.5 mg | 1 | End of RT | −6 | ± 0 | −5 | ± 0 | −4.5 | ± 0 | −4 | ± 0 |
| First follow-up | −10 | ± 0 | −9 | ± 0 | −8.5 | ± 0 | −8 | ± 0 | ||
Abbreviation: RT = radiation therapy.