Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Gene and protein expression analysis of hepatic efflux transporters involved in APAP biotransformation and disposition. A) mRNA levels of Mrp2, Mrp3, and Mrp4; B) Protein expression of Mrp4 from crude liver membrane fractions. Data are presented as mean ± S.E.M. (p ≤ 0.05). An asterisk “*” denotes significant difference between WT and Mrp4−/− mice. A pound “#” denotes significance between 0 h time point and other time points in WT mice.
