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Analysis of hepatic glutathione content and expression of glutathione-related genes and proteins in WT and Mrp4−/− mice. A) mRNA levels of Gclc and Gclm; B) Western blot analysis of Gclc and Gclm; C) Hepatic non-protein sulfhydryl (NPSH) levels. Data are presented as mean ± S.E.M. (p ≤ 0.05). An asterisk “*” denotes significant difference between WT and Mrp4−/− mice.
