Table 1.

Histopathological score of mice livers. Liver sections were incidence and severity scored for degenerative and necrotic changes and scored on a scale of 0–5; 5 being most severe injury and 0 indicative of no injury. Data were tabulated to indicate the number of mice in each group with a given score. Additionally, mice survival rates for each group were also included in the table. Data were ranked prior to statistical analysis. An asterisk “*” denotes significant difference between WT and Mrp4^−/− mice.

	Histological Grade (WT mice)
ID	0	1	2	3	4	5	Percent ≥ 2	% Survival
Veh	5						0	100 (5/5)
12 hr			5				100	100 (5/5)
24 hr			3	2			100	100 (5/5)
48 hr		2	2				50	80 (4/5)
	Histological Grade (Mrp4−/− mice)
ID	0	1	2	3	4	5	Percent ≥ 2	% Survival
Veh	5						0	100 (5/5)
12 hr	1	4					0*	100 (5/5)
24 hr		2	3				60*	100 (5/5)
48 hr		3	2				40	100 (5/5)