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. 2018 Aug 27;26(2):334–339. doi: 10.1016/j.sjbs.2018.08.024

Table 1.

Measurements of expression of biomarkers in cardiovascular diseases and healthy controls.

Variables Control Patients P value (P < 0.05)
Stress variable biomarkers
MDA (nmol/ml) 1.36 ± 0.031 5.44 ± 1.09 0.018
Nitric oxide (ng/ml) 19.19 ± 2.31 55.72 ± 2.16 0.011
Ages (ng/ml) 0.85 ± 0.04 2.74 ± 0.25 0.000
AOPPS (ng/ml) 83.05 ± 7.31 132.07 ± 13.79 0.011
eNOS (U/L) 11.28 ± 1.34 15.5 ± 1.64 0.004



Lipid profile biomarkers
Total cholesterol (mmol/L) 4.45 ± 0.971 5.48 ± 0.33 0.047
Triglycerides (mmol/L) 1.24 ± 0.15 2.59 ± 0.53 0.037
LDL (mmol/L) 2.31 ± 0.091 2.47 ± 0.19 0.013
HDL (mmol/L) 1.74 ± 0.017 1.39 ± 0.031 0.017



Inflammatory biomarkers
IL-Iα (pg/ml) 5.68 ± 0.53 6.64 ± 0.78 0.081
TNF-α (pg/ml) 29.57 ± 2.12 32.16 ± 3.79 0.017
MMP-11 (ng/ml) 45.6 ± 2.71 98.69 ± 7.77 0.017



Anti-oxidative biomarkers
SOD (µg/ml) 0.46 ± 0.003 0.24 ± 0.0021 0.041
Glutathione (µg/ml) 9.77 ± 1.73 4.91 ± 0.077 0.036
Catalase (µmol/mol of protein) 4.27 ± 0.007 1.43 ± 0.011 0.018
Vitamin E (µg/ml) 2.95 ± 0.66 2.19 ± 0.73 0.010
GPx (µmol/ml) 1.59 ± 0.007 2.33 ± 0.021 0.023
GRx (µmol/ml) 7.3 ± 1.67 6.03 ± 1.21 0.029