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. 2019 Aug 30;9:12611. doi: 10.1038/s41598-019-48283-1

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Best scoring maximum likelihood phylogenetic analysis of von Willebrand A domain sequences. The clade containing the sushi domain sequence of G. chorda was used as the outgroup. Bootstrap values <50 removed. Scale bar indicates the branch length for 0.7 aa substitutions. *Denotes full protein sequences that are likely to be secreted, and therefore extracellular. ^—Denotes incomplete or partial sequences. All other sequences in the tree are predicted to be intracellular and/or not secreted. CCA names are shown in bolded red and other noncalcifying red algae species are in blue.