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. 2019 Aug 9;25:104373. doi: 10.1016/j.dib.2019.104373

Specifications Table

Subject Chemistry (General)
Specific subject area Bioorganic and Medical Chemistry
Type of data Images
Graphs
Figures
How data were acquired NMR spectroscopy (JNM-ECX400P, JEOL), microscopy (Olympus's CLX41), western blot imaging system (LAS500, AB Biosciences), microplate reader (VersaMax, Molecular Devices).
Data format Analyzed.
Parameters for data collection Synthesis and cell plasticity/anti-cancer activity after treatment with a novel indirubin derivative, LDD-1819.
Description of data collection The parameters were as follows: 1) 1H NMR spectra of the chemical structure of compound LDD-1819. 2) Cell viability after LDD-1819 treatment. 3) Microscopic observation of myotube cellularization. 4) Quantitative PCR analysis of gene expression related to myogenesis, apoptosis or cancer cell invasion. 5) Inhibition activity against glycogen synthase kinase-3 β and aurora kinase A.
Data source location Gwangju
Republic of Korea (South Korea).
Data accessibility With the article
Related research article Author's name: Kim WH, Jeong P, Kim SW, Cho H, Lee JM, Seo S, Shen H, Ahn Y, Jung DW, Kim YC, Williams DR.
Title: A novel indirubin derivative that increases somatic cell plasticity and inhibits tumorigenicity
Journal: Bioorganic & Medicinal Chemistry.
https://doi.org/10.1016/j.bmc.2019.05.025