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RG7112 pretreatment does not adversely affect treatment outcomes. (Upper) Transplant tumor growth in wild-type mice carrying MMTV-Wnt1 tumors with wild-type p53 with and without RG7112 treatment. (Lower) Transplant tumor growth in wild-type mice carrying MMTV-Wnt1 tumors with mutant p53R172H with and without RG7112 treatment.
