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. 2019 Jul 24;116(35):17419–17428. doi: 10.1073/pnas.1904480116

Fig. 3.

Fig. 3.

Viperin deficiency enhances thermogenesis and leads to cold tolerance. (A) Rectal temperature of 21-wk-old WT and viperin KO mice during chronic cold exposure for 7 d (n = 4–7). (B–E) Gross weights of adipose tissues (n = 4–7) (B), relative mRNA levels of thermogenesis- and fatty acid β-oxidation–related genes in adipose tissues (n = 4–7) (C), protein expression of viperin and UCP1 in the BAT (n = 3) (D), and immunohistochemical staining for UCP1 in adipose tissues (Scale bar: 200 μm) (E) of WT and viperin KO mice after chronic cold exposure.