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. 2019 Aug 30;18:80. doi: 10.1186/s12940-019-0522-2

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Associations between pre-implantation (n = 125) and post-implantation (n = 121) early pregnancy biomarker concentrations and implantation-based length of gestation. Pre-implantation (white dots) hazard ratios represent the risk of birth for women with pre-implantation measured biomarker concentrations above the median compared with those below the median (reference) and post-implantation (black dots) hazard ratios represent the risk of birth for women with post-implantation measured biomarker concentrations above the median compared with those below the median (reference). Hazard ratios < 1.0, indicate a reduced risk of delivery (i.e., longer gestation) and hazard ratios > 1.0 indicate increased risk of delivery (i.e, shorter gestation)