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. 2019 Aug 31;16:175. doi: 10.1186/s12974-019-1557-6

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Post-stroke administration of atRA afforded efficient protection against cerebral ischemia. a Schematic diagram showing the time course of atRA treatment after ischemic stroke. b Infarct volume of mice was quantified with TTC (red)-stained coronal sections (N = 6 mice per group). ***P ≤ 0.001, versus PBS-treated group in t test. c Neurological deficit score was assessed right after reperfusion and 1d after tMCAO (N = 6 mice per group). *P ≤ 0.05, versus PBS-treated group in two-way ANOVA