Table 1.
Summary features MMTVT cases (1943-2018)
| N° | Year | Author (Reference) | N° Cases | Age Years | Asbestos Exposure (latency in years) | Follow Up Months | Side-Laterality | Histologic Subtype | Recurrence Months | Clinical Presentation Onset |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 1943 | Evans [4] | 2 | 66 | NA | 2 | LEFT | NA | NA | MASS |
| 53 | NA | NA | LEFT | NA | NA | SMALL NODULE PAINLESS | ||||
| 2 | 1945 | Robinson [28] | 2 | 30 | NA | NA | NA | NA | NA | NA |
| 28 | NA | NA | NA | NA | NA | NA | ||||
| 3 | 1947 | Patterson [29] | 1 | NA | NA | NA | NA | NA | NA | NA |
| 4 | 1949 | Foote [30] | 1 | NA | NA | dead | NA | NA | metastasis | NA |
| 5 | 1949 | Fajers [5] | 5 | 27 | NA | NA | RIGHT | NA | NA | NA |
| 35 | NA | NA | LEFT | NA | NA | NA | ||||
| 50 | NA | NA | LEFT | NA | NA | NA | ||||
| 45 | NA | NA | RIGHT | NA | NA | NA | ||||
| 58 | NA | Na | RIGHT | NA | NA | NA | ||||
| 6 | 1958 | Reynolds [31] | 1 | 45 | NO | 6 alive | RIGHT | papillary epithelioid | NA | LARGE MASS HYDROCELE |
| 7 | 1968 | Kozlowski [32] | 1 | 63 | NA | NA | spermatic cord | biphasic | NA | MASS |
| 8 | 1968 | Abell [9] | 2 | 78 | NA | 45 dead | NA | biphasic | metastasis | NA |
| 70 | NA | 16 dead | NA | biphasic | metastasis | NA | ||||
| 9 | 1969 | Kasdon [33] | 2 | 58 | NA | 36 dead | RIGHT | papillary epithelioid | 12 | HYDROCELE |
| 72 | NA | 36 recurrence | RIGHT | papillary epithelioId | 5 | HYDROCELE | ||||
| 10 | 1969 | Arlen [34] | 1 | 40 | NA | 216 | LEFT spermatic cord | NA | metastasis | MASS |
| 11 | 1973 | Johnson [35] | 1 | 23 | NA | 3 | RIGHT | papillary epithelioid | 3 alive | SWELLING AND MILD DISCOMFORT |
| 12 | 1975 | Fishelovitch [36] | 1 | 60 | NA | 12 alive | LEFT | papillary epithelioid | NO | SWELLING, HYDROCELE |
| 13 | 1976 | Fligiel [37] | 1 | 68 | pipe insulator for 40 years (pleural plaque) | 20 dead | RIGHT | papillary epithelioid | NA | PAIN AND SWELLING |
| 14 | 1976 | Pugh [38] | 2 | NA | NO | 48 alive | NA | papillary epithelioid | NO | HYDROCELE |
| NA | NO | 84 | NA | papillary epithelioid | 84 recurrence | HYDROCELE | ||||
| 15 | 1976 | Pizzolato [39] | 1 | 57 | Sugar raffinery worker | 41 dead | RIGHT | papillary epithelioid | 12 recurrence | URETHRAL STRUCTURE, SECONDARY URINARY EXTRAVASION WITH URETHRITIS AND RECURRENT INGUINAL HERNIA |
| 16 | 1977 | Eimoto [40] | 1 | 35 | NO | 2 dead | LEFT | fibrous | NA | SWELLING |
| 17 | 1977 | Tuttle [41] | 1 | 37 | NA | NA | RIGHT spermatic cord | fibrous | NA | MASS |
| 18 | 1978 | Sinha [42] | 1 | 65 | NA | 24 alive | RIGHT | papillary epithelioid | NA | SWELLING |
| 19 | 1978 | Jaffe [43] | 1 | 77 | NO | 12 dead | LEFT | papillary epithelioid | Local recurrence | SWELLING |
| 20 | 1981 | Benisch [44] | 1 | 64 | NO | 8 | SCROTUM NA | fibrous | NO | MASS |
| 21 | 1981 | Kossow [14] | 1 | 50 | NA | 24 NED | RIGHT | papillary epithelioid | NO | MASS |
| 22 | 1981 | Blitzer [45] | 1 | 74 | NA | 30 | LEFT spermatic cord | NA | NO | PAINLESS, MASS |
| 23 | 1982 | Japko [46] | 1 | 30 | Insulator for 8 years | 6 NED | RIGHT | Biphasic | NO | SWELLING |
| 24 | 1982 | Chen [47] | 1 | 64 | NA | 30 dead | RIGHT | Biphasic | 24 recurrence | SWELLING |
| 25 | 1982 | Hollands [48] | 1 | 63 | NA | 24 | RIGHT TESTIS | Biphasic | 12 recurrence | HYDROCELE, SWELLING |
| 26 | 1982 | Slaysman [49] | 1 | 20 | NA Maffucci Syndrome | NA | bilateral | papillary epithelioid | Recurrence bilateral | SWELLING |
| 27 | 1983 | Zidar [50] | 1 | 63 | NA | 32 | NA | papillary epithelioid | NA | NA |
| 28 | 1983 | Mc Donald [51] | 2 | 21 | NA | 24 | RIGHT HEMI-SCROTUM bilateral | papillary epithelioid | 24 recurrence | PAINFUL GRADUAL ENLARGMENT |
| 29 | NA | 20 NED | RIGHT HEMI-SCROTUM | papillary epithelioid | NO 20 | PAINFUL GRADUAL ENLARGMENT | ||||
| 29 | 1983 | Van Der Rhee [52] | 1 | 86 | NO | 36 dead | LEFT HEMI-SCROTUM | papillary epithelioid | 12 recurrence | HAEMATOSCROTUM |
| 30 | 1984 | Antman [53] | 6 | 58 | pipefitter | 60 | LEFT INGUINAL | papillary solid polypoid tissue | 60 metastasis | HYDROCELE, INGUINAL HERNIA |
| 73 | shipyard plumber for 25 years | 33 dead | RIGHT | papillary epithelioid | 12 metastasis | HYDROCELE | ||||
| 23 | NA | 180 | LEFT | NA | 180 metastasis | SLOWLY ENLARGEMENT | ||||
| 63 | machinist for 20 years | 48 dead | LEFT | papillary epithelioid | 4 metastasis | MASS | ||||
| 52 | NO | 24 dead | RIGHT | papillary epithelioid | 14 metastasis | MASS | ||||
| 43 | construction worker for 16 years | 48 NED | RIGHT | papillary epithelioid | NO | EPIDIDIMITE | ||||
| 31 | 1984 | Yamanishi [54] | 1 | 34 | NA | 6 | RIGHT | biphasic | NO | MASS |
| 32 | 1984 | Khan [55] | 1 | 42 | NO | 9 dead | RIGHT epididymis | biphasic | 6 metastasis | PAINFULL, SWELLING |
| 33 | 1985 | Vakalikos [56] | 1 | 26 | NA | 12 NED | RIGHT | papillary pseudotu-bular | NO 12 | SWELLING INGUINAL |
| 34 | 1985 | Ehya [57] | 1 | 63 | NA | 52 | LEFT | papillary epithelioid | 50 metastasis | HYDROCELE |
| 35 | 1986 | Karunaharan [58] | 1 | 40 | plastic fenolica worker for 20 years | 14 dead | RIGHT | glandular structure papillary epithelioid | 9 metastasis 12 local recurrence | IRREGULAR MASS |
| 36 | 1986 | Petersen [59] | 1 | 51 | NA | 30 | NA | NA | 30 alive recurrence | NA |
| 37 | 1987 | Cartwright [60] | 1 | 49 | NA | 4 | RIGHT | papillary epithelioid | 24 metastasis | HYDROCELE |
| 38 | 1987 | Fitzmaurice [61] | 1 | 72 | NA | 18 NED | LEFT | papillary epithelioid | NO 18 | SWELLING |
| 39 | 1988 | Linn [62] | 1 | 20 | NA | NA | LEFT | papillary epithelioid | NA | PAIN, SWELLING |
| 40 | 1988 | Prescott [63] | 1 | 61 | Pleural plaques | 21 dead | LEFT |
Biphasic papillary, pseudo-glandular component |
8 Local recurrence metastasis |
HYDROCELE |
| 41 | 1988 | Velasco [64] | 1 | 14 | NA | 24 | LEFT | papillary epithelioid | NO 24 | ABDOMINAL MASS |
| 42 | 1989 | Tyagi [65] | 1 | 79 | Shipyard worker | 24 dead | LEFT | papillary epithelioid | metastasis | SWELLING |
| 43 | 1989 | Grove [27] | 66 | Carpenter for 10 years | 42 | RIGHT | papillary epithelioid |
24 metastasis 42 alive local recurrence |
SWELLING HYDROCELE |
|
| 79 | NO | 60 dead | RIGHT | epithelial papillary | 60 Prostatic metastasis | MASS | ||||
| 58 | NO | 108 NED | LEFT | Tubule papillary | 108 NED | HYDROCELE | ||||
| 44 | 1990 | Kamiya [66] | 1 | 32 | NO | 5 | LEFT | papillary | NO 5 | ELASTIC AND INDOLENT TUMOR |
| 45 | 1990 | Smith [67] | 1 | 57 | NO | alive | LEFT | papillary epithelioid | 48 Local recurrence metastasis | SWELLING |
| 46 | 1990 | Carp [23] | 1 | 54 | NO | 64 dead | LEFT | papillary epithelioid | 38 Local recurrence metastasis | MASS |
| 47 | 1991 | Kuwabara [68] | 1 | 60 | NO | 65 dead | RIGHT | Biphasic | 60 metastasis | SWELLING |
| 48 | 1992 | Pfister [69] | 1 | 7 | NA | 16 | LEFT | papillary epithelioid | NO 16 | SWELLING |
| 49 | 1992 | Adler [70] | 1 | 62 | occupational | 12 | RIGHT | NA | NO 12 | PAINFUL ENLARGEMENT |
| 50 | 1992 | Serio(7 [71] | 1 | 69 | railway cleaner for 10 years | 10 | LEFT | tubulo-papillary | NO 10 | SWELLING |
| 51 | 1992 | Noble [72] | 1 | 62 | NA | NA | LEFT | papillary epithelioid | NA | SWELLING, HYDROCELE |
| 52 | 1992 | Fields [73] | 1 | 91 | Steel industry worker indirect exposure | NA | NA | Biphasic | NA | SWELLING |
| 53 | 1994 | Moch [74] | 1 | 80 | NO | 25 NED | RIGHT | papillary epithelioid | NO | PAINLESS SWELLING |
| 54 | 1994 | Saw [75] | 1 | 63 | Occupational for 7 years [20] | 6 | LEFT | Biphasic | NO 6 | HYDROCELE |
| 55 | 1994 | Reynard [76] | 1 | 76 | NA | NA | RIGHT | tubulo-glandular | 1 recurrence | PAINLESS SWELLING |
| 56 | 1994 | Wenger [77] | 1 | 25 | NA | NA | RIGHT | NA | NA | PAINFUL MASS |
| 57 | 1994 | Watanabe [78] | 1 | 67 | Insulator for 17 years asbestosis | 10 dead | LEFT | biphasic | multifocal | NA |
| 58 | 1995 | Amin [79] | 1 | 59 | NO | 189 | RIGHT | papillary epithelioid | NO 188 | PAINLESS SWELLING |
| 59 | 1995 | Magoha [80] | 1 | NA | NA | NA | NA | fibrous | NA | NA |
| 60 | 1995 |
Huncharek [81] |
1 | 45 | insulator Electrical power plant | 144 | RIGHT | epithelial | NO | PAINLESS MASS |
| 61 | 1995 | Umekawa [82] | 1 | 67 | NO | 8 dead | RIGHT | epithelial | 6 metastasis | SWELLING |
| 62 | 1995 | Eden [83] | 2 | 62 | NO | 6 | LEFT | NA | NO 6 | HYDROCELE |
| 76 | Chemist for 10 years | 27 alive | LEFT | epithelial | 6 recurrence | HYDROCELE | ||||
| 63 | 1995 | Joseph [84] | 1 | 26 | NA | NA | LEFT | NA | NA | TWO PINK TO-PURPLE NODULES |
| 64 | 1995 | Lopez [85] | 1 | 47 | NA | 36 | NA | papillary epithelioid | NO 36 | HYDROCELE |
| 65 | 1995 | Jones [86] | 11 | 75 | NA | Lost follow up | NA | epithelial | NA | HYDROCELE |
| 12 | NA | 12 ned | NA | epithelial | NO 12 | HYDROCELE | ||||
| 39 | NO | 3 | NA | epithelial | NA | PARATESTICULAR MASS | ||||
| 50 | NO | 24 | NA | epithelial | 24 local recurrence | HYDROCELE | ||||
| 41 | NO | 3 | NA | biphasic | NA | PARATESTICULAR MASS | ||||
| 65 | NA | 180 | NA | biphasic | 180 metastasis | PARATESTICULAR MASS | ||||
| 76 | pipe fitter for 10 years | 48 dead | NA | biphasic | NA | HYDROCELE | ||||
| 58 | NA | 36 dead | NA | biphasic | NA | HYDROCELE | ||||
| 67 | NO | 3 | NA | biphasic | NA | PARATESTICULAR MASS | ||||
| 70 | NA | 48 dead | NA | epithelial | NA | HYDROCELE | ||||
| 42 | NA | 24 | NA | epithelial | Alive with disease | HYDROCELE | ||||
| 66 | 1996 | Ahmed [87] | 1 | 80 | dock worker for 10 years | 24 dead | LEFT | papillary epithelioid | 3 local recurrence | HYDROCELE |
| 67 | 1996 | Ascoli [88] | 1 | 55 | Insulator | 6 | RIGHT | biphasic | NA | SWELLING |
| 68 | 1996 | Mathew [89] | 2 | 70 | NA | 3 dead | LEFT | NA | spinal metastasis | SWELLING |
| 58 | NA | 2 dead | RIGHT | NA | spinal metastasis | ENLARGMENT | ||||
| 69 | 1997 | Berti [90] | 1 | 75 | NO | 15 | LEFT | papillary epithelioid | NO 15 | HYDROCELE |
| 70 | 1997 | Agapitos [91] | 2 | 60 | NA | 20 | LEFT | biphasic | NA | SWELLING |
| 84 | NA | 10 | LEFT | biphasic | NO 10 | HYDROCELE | ||||
| 71 | 1997 | Khan [92] | 1 | 6 | NA | 24 | BILATERAL | papillary epithelioid | NO 24 | HYDROCELE |
| 72 | 1998 | Gupta SC [93] | 1 | 36 | NO | 10 | RIGHT | papillary epithelioid | 1,5 metastasis | HYDROCELE |
| 73 | 1998 | Lee [94] | 2 | 45 | NA | 4 | RIGHT | NA | 4 metastasis | HYDROCELE |
| 66 | NA | 6 | LEFT | papillary epithelioid | NO 6 | HYDROCELE | ||||
| 74 | 1998 | Plas [95] | 1 | 14 | NO | 12 | RIGHT | papillary epithelioid | NO 12 | ENLARGEMENT |
| 75 | 1999 | Kanazawa [96] | 1 | 38 | maintenance air conditioning system for 20 years | 156 | BILATERAL | epithelial | 36 local recurrence | INGUINAL HERNIA |
| 76 | 1999 | Harmse [97] | 1 | 70 | NO | 120 | RIGHT | epithelial | NA | MASS |
| 77 | 1999 | Gupta NP [98] | 2 | 69 | NA | 18 dead | RIGHT | biphasic | metastasis | SWELLING |
| 51 | NA | 5 dead | LEFT | biphasic | metastasis | ENLARGEMENT | ||||
| 78 | 2000 | Fujisaki [99] | 1 | 32 | NO | 36 | RIGHT | epithelial | NO 36 | SWELLING |
| 79 | 2000 | Poggi [100] | 1 | 47 | NA | 8 | RIGHT | epithelial | NA | PARATESTICULAR MASS |
| 80 | 2000 | Attanoos [13] | 3 | 71 | dockyard crane driver for 20 years (ASBESTOS BODIES) | NA | RIGHT | biphasic | NA | HYDROCELE |
| 77 | NO | 50 | LEFT | epithelial | NA | MASS | ||||
| 33 | NO | 37 | LEFT | epithelial | NA | MASS | ||||
| 81 | 2000 | Ferri [101] | 1 | 64 | NA | 36 | NA | epithelial | NA | OSTRUZIONE CERVICO-URETRALE |
| 82 | 2001 |
Wolanske [102] |
1 | 71 | NO | 3 | RIGHT | NA | NO 3 | NODLE |
| 83 | 2001 | Sebbag [103] | 2 | 34 | NO | 62 alive | LEFT | epithelial | NO 6O | INGUINAL MASS |
| 19 | NO | 24 dead | LEFT | epithelial | 11 recurrence | SCROTAL MASS | ||||
| 84 | 2001 | Gurdal [104] | 1 | 67 | NO | 30 | RIGHT | epithelial | 24 recurrence | HYDROCELE RECIDIVANTE |
| 85 | 2002 | Abe [105] | 1 | 81 | NO | 12 dead | LEFT | epithelial | 7 metastasis | HYDROCELE |
| 86 | 2002 | Bruno [106] | 1 | 85 | NO | NA | RIGHT HEMI-SCROTUM | epithelial | NA | SWELLING |
| 87 | 2002 |
Iczkowski [107] |
1 | 71 | NO | 26 dead | LEFT HEMI-SCROTUM | epithelial | 19 liver metastasis | PAINFULL SWELLING |
| 88 | 2003 | Black [108] | 1 | 67 | NA | 36 dead | RIGHT | epithelial | 3 recurrence | HYDROCELE |
| 89 | 2003 | Garcia de Jalon [109] | 1 | 78 | carpenter | 3 | RIGHT | tubulo-papillary | 3 metastasis | INCREASE IN THE VOLUME THE TESTIS |
| 90 | 2004 | Pelzer [110] | 1 | 21 | NO | 24 | BILATERAL | epithelial | NA | RECURRENT PAIN |
| 91 | 2004 | Sawada [111] | 1 | 48 | NO | 72 | RIGHT | biphasic | NO 72 | SWELLING |
| 92 | 2004 | Mishra [112] | 1 | 75 | NA | NA | NA | NA | NA | NA |
| 93 | 2004 | Shimada [113] | 1 | 64 | NO | 18 | RIGHT | biphasic80% sarco-matoid | NO | SWELLING |
| 94 | 2005 | Wang [114] | 1 | 81 | NO | NA | RIGHT | tubulo-papillary | NA | SCROTAL MASS |
| 95 | 2005 | Gorini [115] | 2 | 67 | maintenance of locomotives for 30 years [42] | 24 | LEFT | epithelial | NO 24 | MASS |
| 80 | maintenance of tractors for 6 years [67] | 24 | RIGHT | biphasic | NA | SWELLING | ||||
| 96 | 2005 | Spiess [116] (no individual data) | 5 | 57-83 | 4 | 5-68 (4 dead 1 disease free survival 68) | NA | NA | Metastasis in 4 cases | NA |
| 97 | 2006 |
Van Apeldoorn [117] |
1 | 83 | NO but with pleural thickening at CT | 1 dead | RIGHT | epithelial | liver metastasis |
SCROTAL ENLARGEMENT Chyluria |
| 98 | 2006 | Schure [118] | 3 | 45 | NO | 48 | LEFT | NA | NO 48 | SWELLING |
| 35 | NO | 4 dead | LEFT | NA | 2 metastasis | MASS INGUINO-SCROTAL | ||||
| 26 | NO | 18 | LEFT | NA | NO 18 | INGUINAL MASS | ||||
| 99 | 2006 |
Winstanley [119] |
18 | 54 | NO | 12 dead | RIGHT | NA | NA | FOLLOWING A FALL |
| 56 | Dockyard worker | 60 | NA | NA | 60 metastasis | SOVRAPUBIC MASS | ||||
| 59 | NO | 24 dead | LEFT | NA | NA | RECURRENT HYDROCELE | ||||
| 52 | NO | 48 | LEFT | NA | NO 48 | RECURRENT HYDROCELE | ||||
| 49 | NA | 24 | NA | NA | NO 24 | HYDROCELE | ||||
| 79 | NA | 1 | LEFT | NA | NO 1 | HYDROCELE | ||||
| 70 | NA | 12 dead | RIGHT | NA | NA | BLOOD STAINED HYDROCELE | ||||
| 62 | NA | 24 dead | LEFT | NA | NO | RECURRENT HYDROCELE | ||||
| 45 | NA | 6 | LEFT | NA | NO 6 | SWELLING TESTICULAR | ||||
| 65 | NA | 60 | RIGHT | NA | NO 60 | HYDROCELE | ||||
| 75 | NO | 36 | LEFT | NA | NA | HYDROCELE | ||||
| 73 | NO | 12 dead | LEFT | NA | 12 metastasis | TESTICULAR SWELLING | ||||
| 45 | NA | 72 | NA | NA | NO 72 | NA | ||||
| 58 | NO | 36 | LEFT | NA | NO 36 | HYDROCELE HISTORY E YEARS | ||||
| NA | NA | NA | NA | NA | NA | NA | ||||
| NA | NA | NA | NA | NA | NA | NA | ||||
| NA | NA | NA | NA | NA | NA | NA | ||||
| NA | NO | NA | NA | NA | NA | NA | ||||
| 100 | 2007 | Al Qahtani [120] | 1 | 39 | NA | 84 | LEFT | NA | NO 84 | HYDROCELE |
| 101 | 2007 | Liguori [121] | 1 | 68 | NA | 70 | LEFT | epithelial | 24 recurrence | INGUINAL MASS |
| 102 | 2007 | Guney [122] | 1 | 45 | NO | 3 | RIGHT | papillary | NO 3 | TESTICULAR MASS |
| 103 | 2008 | Boyum [123] | 1 | 60 | NO | 23 | LEFT | biphasic | NA |
SCROTAL SWELLING RECURRENT EPIDIDYMITIS |
| 104 | 2008 | Candura [124] | 1 | 38 | petrochemical worker for 16 years | 15 | RIGHT | epithelial | NO 15 | HYDROCELE |
| 105 | 2008 | Mathur [125] | 2 | 65 | Farmer | NA | LEFT | papillary | NA | SWELLING |
| 60 | NA | NA | RIGHT | epithelial | NA | SWELLING | ||||
| 106 | 2008 | Ikegami [126] | 1 | 67 | Painting worker | 26 dead | RIGHT | epithelial | 24 liver metastasis | PAINLESS SWELLING |
| 107 | 2008 | Barui [127] | 1 | 42 | NO | NA | RIGHT | tubulo-papillary | NA | SCROTAL MASS |
| 108 | 2008 | Goel [128] | 1 | 65 | Farmer | 72 | LEFT | epithelial | NA | PAINLESS SWELLING |
| 109 | 2009 | Al Salam [129] | 1 | 83 | NO | NA | LEFT | epithelial | NA | SCROTAL SWELLING |
| 110 | 2009 | Baccheta [130] | 1 | 63 | NO | 30 dead | RIGHT | epithelial | NA | NA |
| 111 | 2009 | Chen [131] | 1 | 67 | Occupational [40] | 7 | RIGHT | biphasic | NO 7 | RIGHT HYDROCELE AND LONG-STANDING BILATERAL HYDROCELE |
| 112 | 2009 | De Lima [132] | 1 | 15 | NO | 12 | RIGHT | epithelial | PAINLESS INCREASE IN SCROTUM VOLUME | |
| 113 | 2010 |
Brimo MUMP [11] |
8 | 43 | NA | 108 alive | NA |
papillary tubulo papillary |
108 NED | HYDROCELE |
| 49 | NA | 24 alive | NA |
papillary tubulo papillary |
24 NED | HYDROCELE | ||||
| 73 | NA | 8 alive | NA |
papillary tubulo papillary |
8 NED | HYDROCELE | ||||
| 34 | NA | 36 alive | NA |
papillary tubulo papillary |
36 NED | SCROTAL MASS | ||||
| 61 | NA | 60 dead | NA |
papillary tubulo papillary |
18 NED | HYDROCELE | ||||
| 53 | NA | 564 dead | NA |
papillary tubulo papillary |
564 | HYDROCELE | ||||
| 57 | NA | NA | NA |
papillary tubulo papillary |
NA | HYDROCELE | ||||
| 50 | NA | NA | NA |
papillary tubulo papillary |
NA | HYDROCELE | ||||
| 114 | 2010 |
Aggarwal [133] |
1 | 75 | NA | 76 dead | LEFT | NA | 30 recurrence | SCROTAL ENLARGEMENT |
| 115 | 2010 | Bisceglia [134] | 1 | 74 | NO | 101 | RIGHT | tubulo-papillary | 24 recurrence | TESTICULAR PAIN |
| 116 | 2010 | Klaassen [135] | 1 | 37 | NO | 6 | LEFT | papillary epitheliode | 6 NO | MASS |
| 117 | 2011 | Trpkov [12]MUMP | 1 | 57 | NO | 72 NED | NA | papillary epitheliode | NO | HYDROCELE |
| 118 | 2011 | Gupta R [136] | 1 | 80 | NA | NA | RIGHT |
tubulo- papillary |
NA | SWELLING OF 3 YEARS DURATION |
| 119 | 2011 | Park [137] | 1 | 65 | Foundry worker for 4 years | 6 dead | LEFT | papillary | 3 recurrence | PALPABLE MASS |
| 120 | 2011 | Grey Venyo [138] | 1 | 69 | NO | NA | LEFT | epithelial | 2 recurrence | SWELLING |
| 121 | 2011 | Bass [139] | 1 | 64 | worked on a naval vessel | 44 alive | LEFT | papillary | 20 recurrence | SCROTAL SWELLING |
| 122 | 2012 | Ahmed [140] | 1 | 78 | NO | 6 | RIGHT | epithelioid | NO 6 | PAINFUL SWELLING |
| 123 | 2012 | Whan Doo [141] | 1 | 36 | NO | 1 | RIGHT | NA | NO 1 | PAINLESS SWELLING |
| 124 | 2012 |
Abdelrahman [142] |
1 | 54 | Farmer | NA | RIGHT | biphasic | NA | SWELLING |
| 125 | 2012 | Esen [143] | 1 | 38 | NO | 26 | LEFT | epitheloid | NO 26 | PAIN AND SWELLING |
| 126 | 2012 | Bo Hai [144] | 6 | 26 | NO | 24 | LEFT spermatic cord | epithelial | NO 24 | SPERMATIC CORD MASS |
| 67 | NO | 24 | LEFT | epithelial | Local recurrence | SCROTAL MASS, BILATERAL HYDROCELE | ||||
| 57 | NO | 24 |
RIGHT spermatic cord |
epithelial | Local recurrence | MASS | ||||
| 46 | YES | 24 dead | LEFT | epithelial | DOD | ACUTE APPENDIX, TESTIS PAIN | ||||
| 78 | NO | 24 | LEFT | epithelial | Local recurrence | SCROTAL MASS, BILATERAL HYDROCELE | ||||
| 76 | YES | 24 dead | LEFT | epithelial | DOD | SCROTAL MASS | ||||
| 127 | 2012 | Priester [145] | 1 | 71 | NA | 24 dead | RIGHT | epithelial | 17 recurrence | HYDROCELE |
| 128 | 2012 | Heng Yen [146] | 1 | 53 | NO | 36 | LEFT | tubulopapillary | NO 36 | RECURRENT EPIDIDYMITIS, HYDROCELE |
| 129 | 2012 | Mrinakova [147] | 1 | 20 | environmental | 41 | LEFT TESTIS | papillary | NO 41 | PAINLESS HYDROCELE |
| 130 | 2012 | Mensi [148] | 13 | 72 | NA | 8 | RIGHT | epithelial | NA | HYDROCELE AND ENLARGEMENT |
| 73 | Familial for 4 years | 44 | LEFT | biphasic | NA | HYDROCELE | ||||
| 76 | Occupational maintenace worker for 32 years | 9 | LEFT | epithelial | NA | SCROTAL HERNIA | ||||
| 80 | Household for 11 years | 18 | RIGHT | biphasic | NA | HYDROCELE | ||||
| 60 | NA | 15 | RIGHT | epithelial | NA | INGUINAL-SCROTAL HERNIA | ||||
| 82 | Occupational spinner for 32 years | 25 | LEFT | sarcomatous | NA | TESTICULAR MASS | ||||
| 38 | Occupational maintenace worker for 16 years | 33 | RIGHT | epithelial | NA | TESTICULAR PAIN AND SPERMATIC CORD TORSION | ||||
| 69 | NA | 52 | LEFT | desmoplastic | NA | HYDROCELE | ||||
| 85 | NA | 14 | LEFT | poorly differentation | NA | HYDROCELE | ||||
| 69 | NA | 39 | LEFT | sarcomatous | NA | TESTICULAR MASS | ||||
| 76 | Occupatonal textile worker for 11 years | 42 | RIGHT | epithelial | NA | HYDROCELE | ||||
| 77 | Occupational bricklayer for 24 years | 8 | LEFT | epithelial | NA | HYDROCELE | ||||
| 74 | Occupatonal bricklayer for 28 years | 6 | LEFT | epithelial | NA | TESTICULAR MASS, HYDROCELE | ||||
| 131 | 2012 | Vijayan [149] | 1 | 89 | Familial (son asbestosis) | 3 dead | LEFT | papillary | 1 recurrence | SWELLING |
| 132 | 2012 | Shelton [150] | 1 | NA | NA | NA | NA | tubulo papillary | NA | NA |
| 133 | 2012 | Gemba no individual data [151] | 5 | na | 3 /5 (construction, shipbuilding, steel production) | NA | NA | NA | NA | NA |
| 134 | 2013 |
Busto Martin [152] |
1 | 61 | NO | 120 | RIGHT | biphasic | NO 120 | INCREASE OF RIGHT SCROTUM SIZE WITH PAIN |
| 135 | 2013 | Gkentzis [153] | 1 | 55 | NA | NA | LEFT | epitheliod | 24 recurrence | MASS PALPABLE |
| 136 | 2013 | Weng [154] | 1 | 28 | NO | 12 | LEFT |
tubulo papillary |
NO 12 | SCROTAL TENDERNESS AND SWELLING |
| 137 | 2013 | Meng [155] | 1 | 45 | NO | 6 alive NED | LEFT | epitheliod | NO | MASS |
| 138 | 2013 | Rajan [156] | 1 | 18 | NA | 14 dead | LEFT | papillary,multycistic | 10 metastasis | SCROTAL PAIN AND SWELLLING |
| 139 | 2013 | MeisenKothen [157] | 9 | 60 | Occupational asbestos cement pipe and domestic for 10 years [53] | 15 dead | RIGHT | NA | 15 recurrence | NA |
| 70 | Familial domestic occupational mechanic for 30 years [64] | 46 alive | RIGHT | epithelioid | NO 46 | NA | ||||
| 59 | Domestic occupational US navy railroad [48] | 71 alive | RIGHT | epithelioid | NO 71 | MASS | ||||
| 44 | Occupational mining worker for 24 years [26] | 14 dead |
RIGHT Spermatic cord |
epithelioid | 14 DOD | NA | ||||
| 74 | occupational shipping industry for 30 years [58] | 54 dead | RIGHT | biphasic | 24 recurrence | INGUINAL MASS | ||||
| 63 | Occupational automobile manufacturing for 8 years [48] | 1 dead | RIGHT | ephitelioid | 1 metastasis | NA | ||||
| 51 | Hobby and occupational asbestos cement pipe for 7 years [41] | 54 alive | LEFT | epithelioid | NO 54 | HYDROCELE | ||||
| 51 | Occupational petrochemical plant worker and hobby for [31] | 43 alive | RIGHT | NA | NO 43 | NA | ||||
| 65 | Occupational mechanic and hobby for 23 years [49] | 39 | LEFT | epithelioid | NO 39 | NA | ||||
| 140 | 2014 | Lin Nei Hsu [158] | 1 | 76 | 50 years house environmental residential | 8 | RIGHT | biphasic | NO | SWELLING |
| 141 | 2014 | Gomes da Fonseca [159] | 1 | 62 | NO | 5 dead | LEFT | epithelioid | 3 metastasis | ENLARGEMENT |
| 142 | 2014 | Stradella [160] | 1 | 51 | Possible occupational | NA | RIGHT | biphasic | NA | HYDROCELE |
| 143 | 2014 | Yang [161] | 1 | 68 | Farmer | 6 | RIGHT | epithelioid | NO | PAINFUL |
| 144 | 2015 | Akin [162] | 1 | 49 | NO | 48 | LEFT | papillary | NA | TESTICULAR MASS |
| 145 | 2015 | Bandyopadhyay [163] | 1 | 40 | Farmer | NA | NA | papillary | NA | SCROTAL SWELLING |
| 146 | 2015 |
Jankovichova [164] |
1 | 67 | Environmental residential roof eternit and occupational lorry driver construction material | 44 | LEFT | epithelioid | 14 local recurrence | HYDROCELE |
| 147 | 2015 | Silverio [165] | 1 | 82 | NA | NA | NA | NA | NA | NA |
| 148 | 2015 | D’Antonio [166] | 1 | 80 | Occupational railway workers | 12 | RIGHT spermatic cord |
tubulo- papillarymm |
NO 12 | PAINLESS MASS |
| 149 | 2015 | Segura [167] Gonzales | 1 | 58 | NO | 6 | LEFT | epithelioid | NO 6 | SWELLING |
| 150 | 2015 | Alesawi [168] | 1 | 69 | NO | 12 | RIGHT |
tubulo- papillary |
NO 12 | HYDROCELE |
| 151 | 2016 | Hispan [169] | 1 | 93 | Occupational aluminum factory for 40 years | NA | LEFT |
tubulo- papillary |
NA cutaneous metastasis | MUTIPLE NODULES |
| 152 | 2016 |
Mrinakova [170] |
2 | 67 | Occupational environmental | 62 | LEFT |
tubulo- papillary |
24 recurrence | HYDROCELE |
| 20 | environmental | 91 | LEFT | epithelioid | NO 91 | HYDROCELE | ||||
| 153 | 2016 | Ahmed [171] | 1 | 45 | Occupaional truck driver | NA | spermatic cord | biphasic | NA | SWELLING |
| 154 | 2016 |
Andresen [172] |
1 | 60 | Occupational | 27 | RIGHT | NA | 24 recurrence |
SWELLING hydrocele |
| 155 | 2016 | Serio [173] | 2 | 77 | Occupational machines ship | 44 dead | LEFT | epithelioid | 26 recurrence | SWELLING |
| 82 | NO | 63 dead | LEFT | epithelioid | 53 recurrence | hydrocele | ||||
| 156 | 2016 |
Bertolotto [174] |
7 | 64 | NA | NA | RIGHT | epithelioid | NA | SCROTAL ENLARGEMENT |
| 60 | NA | 66 | LEFT | epithelioid | NO 66 | MASS | ||||
| 65 | NA | 132 dead | LEFT | epithelioid | NA | SCROTAL ENLARGEMENT | ||||
| 70 | NA | 24 dead | RIGHT | epithelioid | NA | SCROTAL ENLARGEMENT | ||||
| 82 | NA | 6 | RIGHT | epithelioid | NO 6 | PALPABLE MASS | ||||
| 63 | NA | NA | BILATERAL | NA | NA | SCROTAL ENLARGEMENT | ||||
| 75 | NA | NA | RIGHT | NA | NA | PALPABLE MASS | ||||
| 157 | 2017 | Zhang [175] | 1 | 50 | NA | 24 | LEFT | biphasic | NO 24 | PAINLESS ENLARGEMENT |
| 158 | 2017 | Arda [176] | 1 | 84 | NA | NA | LEFT | epithelioid | NO | SCROTAL SWELLING |
| 159 | 2017 |
Recabal [177] No individual data |
15 | 39-66 | 2/15 | 42 median | NA | papillary | NA | NA |
| 160 | 2017 | Shaikh [178] | 1 | 65 | NO | 24 | BILATERAL | biphasic | NO 24 | BILATERAL PAINLESS SCROTAL SWELLING |
| 161 | 2017 | An [179] | 7 | 74 | NO | NA | NA | biphasic | NA | HYDROCELE |
| 67 | YES | 47 | NA | biphasic | NO 47 | SCROTAL MASS | ||||
| 58 | NO | 65 | NA | epithelioid | NO 65 | SPERMATOCELE | ||||
| 43 | NO | 14 | NA | epithelioid | 14 recurrence | SCROTAL MASS | ||||
| 47 | NO | 155 | NA | NA | NO 155 | HYDROCELE | ||||
| 85 | YES | 19 | NA | epithelioid | NO 19 | HYDROCELE | ||||
| 71 | NO | 15 | NA | NA | NO 15 | HYDROCELE | ||||
| 162 | 2017 |
Maheshwari [180] |
1 | 20 | NO | 16 dead | LEFT | NA | NA | SCROTAL SWELLING |
| 163 | 2018 | Abello [181] | 1 | 80 | NO | 26 | RIGHT | biphasic | 24 recurrence | PAINLESS TESTICULAR MASS |
| 164 | 2018 | Trenti [182] | 1 | 40 | NO | 72 NED | LEFT |
tubulo- papillary epithelioid |
72 NED | HYDROCELE |
| 165 | 2018 | Zhang [183] | 1 | 65 | NO | 72 alive | LEFT | NA | 72 metastasis | HYDROCELE BILATERAL |
| 2018 | Current cases | 4 | 75 | Occupational foundry worker for 4 years [46] | 141 alive | LEFT |
tubulo- papillary epithelioid |
No | MASS HYDROCELE | |
| 77 |
Occupational asbestos cement worker for 23 years asbestosis pleural plaques [45] |
2 dead | LEFT |
tubulo- papillary epithelioid |
2 metastasis | MASS | ||||
| 78 | Occupational ship machinist ship then reclaimed for 3 years [58] | 40 dead | LEFT |
tubulo- papillary epithelioid |
cardiopath | MASS | ||||
| 63 | Occupational mason cutting plates eternit trucker for 14 years [41] | 3 alive | LEFT |
tubulo- papillary epithelioid |
Recent case 3 months alive | MASS HYDROCELE |
LEGEND: NA not available, NED no evidence of disease, DOD dead of disease, CT computer tomography, MUMP mesothelioma uncertain malignant potential