Table 2.

Anticholinesterase activities of the bioactive compounds (V–VIII) isolated from Grewia optiva

Samples	Concentrations(μg/mL)	Percent AChE(mean ± SEM)	AChE IC50(µg/mL)	Percent BChE(mean ± SEM)	BChE IC50(µg/mL)
Compound V	1000	79.13±1.42***	118	78.91±1.61***	123
	500	70.23±1.51***		69.12±2.24**
	250	61.44±2.09***		60.77±1.22***
	125	51.09±2.18**		50.15±2.01**
62.5	41.19±1.71***	40.10±1.13*
Compound VI	1000	83.23±1.11**	76	82.11±2.11**	78
	500	74.29±1.40**		74.13±2.61**
	250	65.21±1.14**		63.43±1.20***
	125	56.11±1.10***		54.25±2.51**
62.5	48.19±3.34***	48.02±2.06**
Compound VII	1000	82.72±2.20**	90	82.23±1.21**	92
	500	71.29±2.57**		71.13±1.81**
	250	63.41±2.14**		62.14±2.13***
	125	54.16±2.28***		53.21±2.11**
62.5	45.77±2.31***	45.18±2.16**
Compound VIII	1000	79.61±2.10**	122	78.23±1.31**	124
	500	71.19±2.37**		71.29±1.10**
	250	62.11±2.41**		61.24±2.10***
	125	50.29±2.10***		50.11±2.16**
62.5	41.71±3.01***	40.60±1.06**
Galanthamine	1000	94.11±1.56	40	93.89±0.81	40
	500	86.17±1.50		85.14±2.06
	250	77.13±1.08		77.08±2.26
	125	64.15±2.70		64.42±1.85
62.5	53.71±2.31	53.52±1.69

Notes: Data presented as (mean ± S.E.M) n=3. Values significantly different as compared to positive control, P>0.05 *P<0.05, **P<0.01, ***P<0.001. Galanthamine was used a positive control.