Table 1:
MIC results of AMB/ATO, LOV combination against 20 strains of R. oryzae
| Strain | Source | MIC of LOV (μg/m) | MIC of ATO (μg/m) | MIC of AMB alone (μg/m) | MIC of AMB in combination with LOV (μg/m) | MIC of AMB in combination with ATO (μg/m) |
|---|---|---|---|---|---|---|
| R. oryzae | Clinical-1 | >16 | 4 | 0.5 | 0.5 | 0.25 |
| R. oryzae | Clinical-4 | >16 | 8 | 0.5 | 0.5 | 0.25 |
| R. oryzae | Clinical-7 | >16 | 16 | 0.5 | 0.25 | 0.031 |
| R. oryzae | Clinical-8 | >16 | 8 | 0.063 | 0.063 | 0.063 |
| R. oryzae | Clinical-9 | >16 | 2 | 0.031 | 0.031 | 0.031 |
| R. oryzae | Clinical-10 | >16 | 8 | 0.5 | 0.5 | 0.25 |
| R. oryzae | Clinical-11 | >16 | 8 | 0.5 | 0.25 | 0.25 |
| R. oryzae | Clinical-12 | >16 | 8 | 1 | 0.5 | 0.25 |
| R. oryzae | Clinical-13 | >16 | 8 | 0.25 | 0.25 | 0.25 |
| R. oryzae | Clinical-14 | >16 | 16 | 0.5 | 0.25 | 0.063 |
| R. oryzae | Clinical-15 | >16 | 8 | 1 | 0.5 | 0.063 |
| R. oryzae | Clinical-16 | >16 | 16 | 1 | 1 | 1 |
| R. oryzae | Clinical-17 | >16 | 16 | 0.5 | 0.5 | 0.031 |
| R. oryzae | Clinical-19 | >16 | >16 | 0.5 | 0.25 | 0.25 |
| R. oryzae | Clinical-20 | >16 | >16 | 0.5 | 0.25 | 0.25 |
| R. oryzae | Environmental-2 | >16 | 8 | 1 | 0.25 | 0.25 |
| R. oryzae | Environmental-3 | >16 | 8 | 1 | 0.25 | 0.063 |
| R. oryzae | Environmental-5 | >16 | 8 | 0.5 | 0.25 | 0.25 |
| R. oryzae | Environmental-6 | >16 | >16 | 0.5 | 0.25 | 0.063 |
| R. oryzae | Environmental-18 | >16 | >16 | 0.063 | 0.063 | 0.063 |
| MIC range | 2–>16 | 0.031–1 | 0.031–1 | 0.031–1 | ||
| MIC50 | 8 | 0.5 | 0.25 | 0.25 | ||
| MIC90 | >16 | 1 | 0.5 | 0.25 | ||
| GM | 9.5 | 0.38 | 0.26 | 0.13 |