Table:
Characteristics of 350 patients who had HIV drug resistance testing
Category | Aurum | Tygerberg |
---|---|---|
Number (Percentage) or Median (interquartile range) |
Number (Percentage) or Median (interquartile range) |
|
Cohort n | 184 | 166 |
Sex | ||
Male | 119 (65) | 47 (28) |
Female | 65 (35) | 119 (72) |
Age, median | 38 (33, 45) | 35 (29, 41) |
CD4 count at ART initiation | 129 (64, 223) | 116 (68, 174) |
Single HIV RNA >1000 | 184 (100) | 166 (100) |
2 consecutive VL>1000 (WHO virologic failure definition) | 88 (48) | 99 (60) |
WHO immunologic failure criteria | 103 (56) | 38 (23) |
Duration of ART at time of resistance testing, months | 20 (11, 31) | 14 (9.2, 24) |
ART regimen at resistance testing | ||
NRTI + lamivudine | ||
AZT | 93 (51) | 26 (16) |
D4T | 53 (29) | 138 (83) |
TDF | 36 (20) | 2 (1.2) |
NNRTI | ||
Efavirenz | 131 (71) | 80 (48) |
Nevirapine | 53 (29) | 87 (52) |