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. 2019 Aug 28;7:e7628. doi: 10.7717/peerj.7628

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©2019 Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.

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The PPI network of DEGs included 297 nodes and 410 edges with minimum required interaction score >0.4 (median confidence). The size of edges change from small to large represents the combined score of nodes change from low to high, the size of nodes represents the count. Red nodes represent up-regulated genes, yellow nodes represent down-regulated genes. PPI, protein–protein interaction; DEG, differentially expressed genes.