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. 2019 Aug 28;7:e7568. doi: 10.7717/peerj.7568

Figure 4. Effect of NR repletion on inflammatory infiltration of aging-relative NAFLD model.

Figure 4

(A–D) Immunohistochemistry staining in liver of aged mice showed the effect of NR supplementation on Kupffer cell accumulation and (I) quantittive analysis. Red arrows show positive brown staining for F4/80 or CD68. (E–H) Protein levels of IL-1β and TNF-α were detected by immunohistochemistry and (J) quantittive analysis. Red arrows show positive brown staining for IL-1β or TNF-α. 200×; Scale bars, 100 µm. Values are mean ± SEM, (n = 5–6 per group). ∗P < 0.05.