Table 1.
Demographics and semen sample collection characteristics across quartiles of SG-adjusted triclosan urinary concentrations (in μg/L) among 262 men (581 urine and 581 semen samples) participating in the EARTH Study.
| Quartile | Q1 | Q2 | Q3 | Q4 | Total | |
|---|---|---|---|---|---|---|
| Median (IQR) of SG-adjusted triclosan concentration, [range] | Non-detectable | 3.25 (2.32,4.57), [0.73, 6.63] | 13.8 (9.62,23.1), [6.80, 41.2] | 191 (79.7,388), [41.3, 2516] | 7.16 (2.55, 40.2) , [<LOD, 2517] | |
| Baseline characteristics for men, N (%) | N=63 (24) | N=58 (22) | N=62 (24) | N=79 (30) | N=262 (100) | P-value |
| Age (years) | 38.0 (6.11) | 36.9 (5.41) | 36.9 (5.41) | 35.7 (4.9) | 36.6 (5.24) | 0.10 |
| BMI, N (%) | 0.32 | |||||
| Underweight | 1 (2) | 0 (0) | 0 (0) | 0 (0) | 1 (0.4) | |
| Normal weight | 18 (29) | 16 (28) | 16 (26) | 30 (38) | 80 (31) | |
| Overweight | 31 (49) | 23 (40) | 27 (44) | 35 (44) | 116 (44) | |
| Obese | 13 (21) | 19 (33) | 19 (30) | 14 (18) | 65 (25) | |
| Race, N (%) | 0.50 | |||||
| Caucasian | 57 (90) | 49 (84) | 52 (84) | 72 (91) | 230 (88) | |
| Black/African American | 2 (3) | 1 (2) | 4 (6) | 1 (1) | 8 (3) | |
| Asian | 4 (6) | 6 (10) | 3 (5) | 4 (5) | 17 (6) | |
| Native American/Alaska Native | 0 (0) | 2 (3) | 3 (5) | 2 (3) | 7 (3) | |
| Education, N (%) | 0.70 | |||||
| Below College | 6 (10) | 6 (10) | 5 (8) | 11 (14) | 28 (11) | |
| College or Graduate Degree | 57 (90) | 52 (90) | 57 (92) | 68 (86) | 234 (89) | |
| Reproductive diseases, N (%) | 9 (14) | 7 (12) | 9 (15) | 19 (24) | 44 (17) | 0.22 |
| Reproductive Surgeries, N (%) | 7 (11) | 1 (2) | 8 (13) | 14 (18) | 30 (11) | 0.02 |
| Smoking Status, N (%) | 0.16 | |||||
| Never | 46 (73) | 31 (53) | 43 (69) | 52 (66) | 172 (67) | |
| Former | 15 (24) | 25 (43) | 18 (29) | 21 (27) | 79 (30) | |
| Current | 2 (3) | 2 (3) | 1 (2) | 6 (8) | 11 (4) | |
| Moderate to vigorous physical activity, hrs/week | 6.25 (10.6) | 4.33 (12.9) | 5.80 (8.88) | 4.23 (5.66) | 5.11 (9.57) | 0.11 |
| Time-varying characteristics for semen samples, n (%) | 151 (26) | 143 (25) | 144 (25) | 143 (25) | 581 (100) | |
| Season of sample collection, April to September | 67 (44) | 54 (38) | 57 (40) | 64 (45) | 242 (42) | 0.54 |
| Sexual Abstinence Time | - | - | 0.77 | |||
| <2 days | 43 (28) | 51 (36) | 50 (35) | 50 (35) | 194 (33) | |
| 2 - 3 days | 72 (48) | 61 (43) | 60 (42) | 57 (40) | 250 (43) | |
| 3 - 4 days | 20 (13) | 18 (13) | 20 (14) | 26 (18) | 84 (14) | |
| >4 days | 16 (11) | 13 (9) | 14 (10) | 10 (7) | 53 (9) | |
| Time between sample collection and analysis | 0.32 | |||||
| ≤30 min | 142 (94) | 138 (97) | 133 (92) | 136 (95) | 549 (94) | |
| > 30 min | 7 (5) | 4 (3) | 4 (3) | 5 (4) | 20 (3) | |
| Missing | 2 (1) | 1 (1) | 7 (5) | 2 (1) | 12 (2) | |
N (%) is presented for categorical/binary variables and mean (standard deviation) is presented for continuous variables.
From Chi-square (or Fisher’s exact test when appropriate) for discrete variables and Kruskal-Wallis for continuous variables.
Reproductive diseases: Report of any of the following: varicocele testicular torsion, testicular injury, undescended testis, hernia, epididymitis, prostatitis & seminal vesicle infection.
Reproductive Surgeries: Report of any of the following: orchidopexy, varicocelectomy, hydrocelectomy, hernia repair, urethral repair, hypospadias repair, sympathectomy & bladder neck surgery.
Includes weight and aerobic exercise and sports.
Summation of the percentages may not add up to 100% due to approximations.
Abbreviations: N; number of participants, n; number of semen samples, EARTH; the Environment and Reproductive Health study, Q; quartile, IQR; interquartile range, SG; specific gravity, BMI; body mass index, hrs; hours, min; minutes.