Table 3.

Tumor physiological parameters [28, 30]

			Value			Unit
	Parameter Definition	Well diffused		Moderately diffused	Poorly diffused
Q	Tumor blood perfusion	60				mL/h
CDNA	DNA concentrations	0.382				μmol/mL
S1	Surface area of tumor cells in the proximal layer	17677		5303	982	cm2
S2	Surface area of tumor cells in the intermediate layer	19445		18070	7660	cm2
S3	Surface area of tumor cells in the distal layer	8053		21802	36532	cm2
VL1e	Intracellular volume of the tumor cells in the proximal layer	3.115		0.935	0.173	mL
VL1em	Intracellular volume of macrophage cells in the proximal layer	0.0078		0.0023	0.0004	mL
VL1i	Interstitial volume of the proximal layer	0.779		0.233	0.0433	mL
VL2e	Intracellular volume of the tumor cells in the intermediate layer	3.427		3.184	1.350	mL
VL2em	Intracellular volume of macrophage cells in the intermediate layer	0.0086		0.0080	0.0034	mL
VL2i	Interstitial volume of the intermediate layer	0.857		0.796	0.337	mL
VL3e	Intracellular volume of the tumor cells in the distal layer	1.419		3.842	6.44	mL
VL3em	Intracellular volume of macrophage cells in the distal layer	0.0036		0.0096	0.0161	mL
VL3i	Interstitial volume of the distal layer	0.355		0.961	1.61	mL