SmAP-suppressed parasites are impaired in their ability to cleave polyP. Adult males were treated with siRNA targeting SmAP or with control siRNA (Control) or with no siRNA (None), as indicated. Seven days later the ability of all worms to cleave polyP was measured. The Pi level (µM, mean ± SD) detected at the 24-hour time point is shown. The SmAP suppressed group generated significantly less Pi compared to either of the control groups, p <0.05 (one-way ANOVA, F=31.07, Df=11). There is no significant (ns) difference between the two control mean values.