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. 2019 Sep;104(9):e385–e387. doi: 10.3324/haematol.2018.212779

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Figure 1. — Time to first albuminuria in patients with and without APOL1 risk variants. Kaplan-Meier curve showing shorter time to albuminuria diagnosis for individuals homozygous for APOL1 G1 or G2 or double heterozygous for G1/G2. APOL1 G1 homozygotes defined as rs73885319=″GG″/rs6090145=″GG″. APOL1 G2 homozygotes defined as rs71785313=″−/−″. APOL1 G1/G2 double heterozygotes defined as G1/G2 (both heterozygotes). Albuminuria defined by first visit with microalbumin creatinine ratio (MCR) ≥30. Analyses adjusted for total HU up to time of albuminuria diagnosis or at time patient was censored. Patients with sickle cell (SS) disease and Sβ0 included in analyses.