Table 4.

Fixed effects estimates with 95% confidence intervals and p-values for age and BMI as regressors for regional [¹¹C]PBR28 log-transformed V_T in a separate subgroup analysis for males (N = 72) and females (N = 68)

Region	Age (β, [CI], p), Male	Age (β, [CI], p), Female	BMI (β, [CI], p), Male	BMI (β, [CI], p), Female
Grey matter	0.006, [0.002,0.010], p = 0.002	−0.002, [−0.008,0.004], p = 0.542	−0.026, [−0.042,-0.010], p = 0.002	−0.017, [−0.035,0.001], p = 0.061
Frontal cortex	0.007, [0.003,0.011], p = 0.001	−0.001, [−0.007,0.005], p = 0.645	−0.024, [−0.040,-0.008], p = 0.004	−0.015, [−0.033,0.003], p = 0.085
Temporal cortex	0.007, [0.003,0.011], p = 0.001	−0.001, [−0.007,0.005], p = 0.745	−0.026, [−0.042,-0.010], p = 0.002	−0.019, [−0.037,-0.001], p = 0.039
Occipital cortex	0.005, [0.001,0.009], p = 0.006	−0.002, [−0.008,0.004], p = 0.462	−0.023, [−0.039,-0.007], p = 0.004	−0.013, [−0.031,0.005], p = 0.123
Parietal cortex	0.006, [0.002,0.010], p = 0.002	−0.002, [−0.008,0.004], p = 0.467	−0.021, [−0.037,-0.005], p = 0.010	−0.012, [−0.030,0.006], p = 0.175
Hippocampus	0.004, [0.000,0.008], p = 0.046	−0.002, [−0.006,0.002], p = 0.399	−0.027, [−0.045,-0.009], p = 0.005	−0.020, [−0.036,-0.004], p = 0.020
Thalamus	0.006, [0.002,0.010], p = 0.007	−0.001, [−0.005,0.003], p = 0.755	−0.022, [−0.040,-0.004], p = 0.011	−0.020, [−0.038,-0.002], p = 0.030