Skip to main content
. Author manuscript; available in PMC: 2020 Oct 15.
Published in final edited form as: Brain Res. 2019 Jul 4;1721:146303. doi: 10.1016/j.brainres.2019.146303

Figure 4.

Figure 4.

Relationship between verbal encoding-related activity in the left HIPP and endogenous levels of DHEAS by sex/reproductive status, a) In MDD, task-related HIPP activity increased with higher levels of DHEAS in postmenopausal women, reaching levels similar to pre/perimenopausal women and men. Brain image displays positive correlation between DHEAS and fMRI BOLD activity in the left hippocampus in postmenopausal women with MDD (to illustrate full spatial extent, findings are displayed at p< 0.05, uncorrected), b) In non-MDD, there was no relationship between task-related HIPP activity and DHEAS levels in any group. Brain image displays positive correlation between DHEAS and fMRI BOLD activity in the left hippocampus in postmenopausal women with no MDD (to illustrate full spatial extent, findings are displayed at p < 0.05, uncorrected). Functional ROI was generated from an anatomically-defined mask of the HIPP (Novel > Repeat). DHEAS levels were natural log transformed.