Table 2.
Hormone assessment of sample by MDD and sex/reproductive status
| Men | Women | Pre/Perimenopause | Postmenopause | Comparisons | |
|---|---|---|---|---|---|
| Median (p25, p75) | Median (p25, p75) | Median (p25, p75) | Median (p25, p75) | ψp < 0,001; *p < 0.05; †p < 0.1 | |
| DHEAS (ug/dL) | |||||
| MDD | 132.0 (99.3, 202.8) | 114.9 (S5.0, 149.0) | 121.0 (71.5, 156.0) | 103.5 (58.8, 126.9) | Men > Women†, Post* |
| Non-MDD | 150.0 (97.1, 198.3) | 87.0 ( 63.1, 129.5) | 85.9 (68.5, 124.7) | 93.6 (56.8, 139.8) | Men > Womenψ, Pre/Periψ, Postψ |
| n.s. | n.s. | n.s. | n.s. | ||
| 17β-Estradiol (pg/ml)a | |||||
| MDD | - | 41.3 (8.9, 84.8) | 53.0 (29.2, 100.9) | 4.3 (3.4, 10.1) | Pre/Peri >Postψ |
| Non-MDD | - | 24.8 (11.8, 90.4) | 60.6 (16.9, 122.5) | 13.7 (5.9, 29.9) | Pre/Peri>Postψ |
| n.s. | n.s. | non-MDD>MDD* | |||
| Progesterone (ng/ml)b | |||||
| MDD | - | 0.18 (0.06, 1.42) | 0.19 (0.08, 3.41) | 0.07 (0.04, 0.38) | Pre/Peri > Post* |
| Non-MDD | - | 0.13 (0.06, 0.33) | 0.20 (0.10, 4.80) | 0.07 (0.05, 0.09) | Pre/Peri >Postψ |
| n.s. | n.s. | n.s. | |||
| FSH (mIU/ml) | |||||
| MDD | - | 12.7 (6.8, 56.6) | 10.1 (6.5, 16.2) | 65.5 (48.2, 73.6) | Post> Pre/Periψ |
| Non-MDD | - | 30.5 (6.6, 68.3) | 9.1 (4.8, 35.0) | 64.2 (43.7, 92.3) | Post> Pre/Periψ |
| n.s. | n.s. | n.s. | |||
a
Missing n=1;
b
Missing n=3
Comparisons by group status were evaluated using nonparametric Wilcoxon rank-sum (n.s. = Not Significant).
p25, p75: 25th and 75th quartiles