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Delivery of TLR7/8a (R848) in cyclodextrin NPs (CDNPs) enhances tumor therapy in the MC38 colon adenocarcinoma mouse model. (a) Scheme to assemble R848 in CDNPs (CDNP-R848). Treatment of mice with CDNP-R848 (b) reduces tumor area, (c) improves survival, and (d) reduces overall tumor burden relative to free R848. Adapted with permission from [11].
