Table 2:

Organ weights determined at the termination of study after 8 weeks of HFD treatment.

Models	Body	Liver	Kidney	WATa	Testis
WT-F	23.75±1.03	0.91±0.04	0.25±0.01	1.13±0.20
Cyp3a-null F	23.88±1.34	0.88±0.04	0.30±0.01***	0.78±0.23
WT-M	35.88±1.22	1.39±0.06	0.40±0.01	3.20±0.36	0.24±0.01
Cyp3a-null M	39.14±0.74*	1.50±0.54*	0.42±0.01	3.57±0.32	0.17±0.02**

^aWhite adipose tissue (WAT)

Data represented as mean +/− SEM (n = 7 or 8). Statistical significance determined by Student’s t-test.

^*Indicates a p-value ≤ 0.05,

^**indicates a p-values ≤ 0.01, and

^***indicates a p-value ≤ 0.001.