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. 2019 Aug 27;11(8):619–637. doi: 10.4254/wjh.v11.i8.619

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©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Gut microbial composition of mice subjected to prolonged high-fat diet-feeding. A: Chao1 and sequence per sample; B: Principal coordinates analysis (PCoA). n = 7 mice per group. Only the feces of Old-high-fat diet-feeding and Old-high-fat diet-feeding mice were analyzed. Data are expressed as mean ± SE. n = 7 per group. HFD: High-fat diet-feeding; LFD: Low-fat diet.