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. 2019 Aug 27;14:6917–6932. doi: 10.2147/IJN.S213084

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© 2019 Wei et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

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Transmission electron microscopy of C-DMSA@VES-g-CSO/VES-g-CS MM (A); particle size distribution of C-DMSA@VES-g-CSO/VES-g-CS MM obtained from dynamic light scattering (B); C-DMSA release profile from micelles in PBS solution (pH=7.4) (C) and particle size changes of C-DMSA loaded micelles stored at 4°C as a function of storage time (D).

Note: Data were presented as mean±SD (n=3).

Abbreviations: C-DMSA, 3-formyl-7-diethylamino coumarin masked meso-dimercaptosuccinic acid; C-DMSA@VES-g-CSO micelles, C-DMSA loaded vitamin E succinate-grafted-chitosan oligosaccharide micelles; C-DMSA@VES-g-CS micelles, C-DMSA loaded vitamin E succinate-grafted-chitosan micelles; C-DMSA@VES-g-CSO/VES-g-CS MM, C-DMSA loaded vitamin E succinate-grafted-chitosan oligosaccharide/vitamin E succinate-grafted-chitosan mixed micelles.