Table 1.
Physicochemical properties of C-DMSA loaded micelles
| Micelles | LE (%) | EE (%) | Particle size (nm) | Zeta potential (mV) | PI |
|---|---|---|---|---|---|
| VES-g-CSO micelles | / | / | 178.5±2.1 | 35.7±3.2 | 0.28 |
| C-DMSA@VES-g-CSO micelles | 7.5±0.2 | 82.8±1.5 | 185.3±6.2 | 30.9±1.9 | 0.21 |
| VES-g-CS micelles | / | / | 116.9±1.1 | 17.3±1.7 | 0.17 |
| C-DMSA@VES-g-CS micelles | 3.1±0.2 | 34.9±1.2 | 120.9±3.1 | 17.3±0.4 | 0.17 |
| VES-g-CSO/VES-g-CS MM | / | / | 124.5±3.5 | 25.6±0.9 | 0.16 |
| C-DMSA@VES-g-CSO/VES-g-CS MM | 6.9±0.3 | 76.6±1.7 | 133.2±4.9 | 24.1±0.1 | 0.16 |
Notes: Data were presented as mean±SD (n=3). “/”means the data is indeterminable.
Abbreviations: LE, loading efficiency; EE, entrapment efficiency; PI, polydispersity index; VES-g-CSO micelles, vitamin E succinate-grafted-chitosan oligosaccharide micelles; VES-g-CS micelles, vitamin E succinate-grafted-chitosan micelles; VES-g-CSO/VES-g-CS MM, vitamin E succinate-grafted-chitosan oligosaccharide/vitamin E succinate-grafted-chitosan mixed micelles; C-DMSA, 3-formyl-7-diethylamino coumarin masked meso-dimercaptosuccinic acid.