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. 2019 Jul 5;27:75–82. doi: 10.1016/j.molmet.2019.07.001

Table 1.

Mean lifespans of C. elegans strains.

Figure Individual Experiments Genotypes Compared # of Worms Mean Lifespan ± SEM (days) % Lifespan Change compared to N2 or as noted p Value Combined p Value compared to N2 or as noted
1H 1 N2 206 14.07 ± 0.35
atgl-1::gfp 202 18.62 ± 0.44 +32.3 <1.0e-10
2 N2 132 15.74 ± 0.44
atgl-1::gfp 82 20.20 ± 0.78 +28.3 7.8e-8
3 N2 90 14.78 ± 0.39
atgl-1::gfp 112 20.87 ± 0.67 +41.2 <1.0e-10 <1.0e-4
2F 1 N2 146 13.90 ± 0.35
eat-2(ad453) 104 18.81 ± 0.80 +35.3 1.0e-3
atgl-1(P87S) 156 13.8 ± 0.30 −0.7 0.5495
eat-2(ad453); atgl-1(P87S) 166 12.58 ± 0.18 −9.5
−33.1 (comp. to eat-2)
1.0e-3
<1.0e-10 (comp. to eat-2)
2 N2 216 13.20 ± 0.33
eat-2(ad453) 187 18.77 ± 0.45 +42.2 <1.0e-10
atgl-1(P87S) 180 14.26 ± 0.24 −8.0 0.0326
eat-2(ad453); atgl-1(P87S) 206 12.58 ± 0.28 −4.7
−33.0 (comp. to eat-2)
0.7903
<1.0e-10 (comp. to eat-2)
3 N2 217 13.3 ± 0.34
eat-2(ad453) 202 20.33 ± 0.51 +52.9 <1.0e-10 <1.0e-4
atgl-1(P87S) 255 12.52 ± 0.17 −5.9 0.85 0.21
eat-2(ad453); atgl-1(P87S) 251 15.43 ± 0.41 +16.0
−24.1 (comp. to eat-2)
4.3e-6
<1.0e-10 (comp. to eat-2)
<1.0e-4 (comp. to eat-2)
3D 1 N2 100 12.0 ± 0.39
daf-2(e1370) 90 27.73 ± 1.7 +131.1 <1.0e-10
atgl-1(P87S) 102 10.92 ± 0.30 −9.0 0.1268
daf-2(e1370); atgl-1(P87S) 110 14.90 ± 0.89 +24.2
−46.3 (comp. to daf-2)
3.3e-3
<1.0e-10 (comp. to daf-2)
2 N2 189 14.46 ± 0.29
daf-2(e1370) 171 28.22 ± 0.81 +95.2 <1.0e-10
atgl-1(P87S) 174 14.16 ± 0.30 −2.1 1
daf-2(e1370); atgl-1(P87S) 155 16.87 ± 0.63 +16.7
−40.2 (comp. to daf-2)
3.0e-4
<1.0e-10 (comp. to daf-2)
3 N2 194 14.07 ± 0.35
daf-2(e1370) 113 29.99 ± 1.65 +113.1 <1.0e-10 <1.0e-4
atgl-1(P87S) 180 14.26 ± 0.24 +1.4 1 0.66
daf-2(e1370); atgl-1(P87S) 134 16.84 ± 0.63 +19.7
−43.8 (comp. to daf-2)
4.1e-3
<1.0e-10 (comp. to daf-2)
<1.0e-4
<1.0e-4 (comp. to daf-2)