Figure 7.

Thermogenic profiling of hairless SKH1 mice. A. EE was measured for mice housed at the temperatures indicated for >48 h (24 and 31 °C) or 24 h (35 °C) (n = 8). B, C. TEWL and rectal body temperatures were also measured for these mice. Data are expressed as mean ± SEM, and statistical analysis was performed with unpaired 2-tailed t tests (****P < 0.0001; ***P < 0.001; **P < 0.01; ns = not significant). D. Representative images show the dynamic range of lipid storage in BAT in mice housed at different ambient temperatures, as assayed by histological analysis (n = 8).