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. 2019 Aug 28;12:6991–7004. doi: 10.2147/OTT.S214881

Figure 2.

Figure 2

Suppression of SNHG8 inhibits Eca109 and TE-1 cell proliferation, migration, and invasion and induces their apoptosis. (A) Si-SNHG8 or si-scramble was transfected into Eca109 and TE-1 cells. SNHG8 expression following the transfection was examined by RT-qPCR. *P<0.05 vs si-scramble. (B) The CCK-8 assay was carried out to evaluate the proliferation of Eca109 and TE-1 cells after transfection of si-SNHG8 or si-scramble. *P<0.05 vs si-scramble. (C) Eca109 and TE-1 cells were transfected with si-SNHG8 or si-scramble and the proportion of apoptotic cells was measured via flow-cytometric analysis. *P<0.05 vs si-scramble. (D, E) Transwell migration and invasion assays uncovered the influence of SNHG8 silencing on the migratory capacity and invasiveness of Eca109 and TE-1 cells. *P<0.05 vs si-scramble.