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. 2019 Aug 28;12:6991–7004. doi: 10.2147/OTT.S214881

Figure 7.

Figure 7

SNHG8 regulates the malignant characteristics of Eca109 and TE-1 cells through the miR-411–KPNA2 axis. (A) The transfection efficiency of the miR-411 inhibitor in Eca109 and TE-1 cells was evaluated by RT-qPCR analysis. The NC inhibitor served as the control. *P<0.05 vs NC inhibitor. (B, C) RT-qPCR and Western blotting were respectively utilized to assess miR-411 and KPNA2 protein expression in Eca109 and TE-1 cells following cotransfection with si-SNHG8 and either miR-411 inhibitor or NC inhibitor. *P<0.05 vs si-scramble. #P<0.05 vs si-SNHG8+NC inhibitor. (D–G) The proliferation, apoptosis, migration, and invasiveness of the aforementioned cells were evaluated by the CCK-8 assay, flow cytometry, and Transwell migration and invasion assays, respectively. *P<0.05 vs si-scramble. #P<0.05 vs si-SNHG8+NC inhibitor.