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. 2019 Aug 28;14:6957–6970. doi: 10.2147/IJN.S214008

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© 2019 Xia et al.

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In vivo blood clearance (A) and tissue biodistribution (B) of different sized gold nanaoparticles (AuNPs) in BALB/c mice after intravenous administration at the dose of 0.5 mg/kg. Blood samples were collected at the indicated time points, and the Au content in blood was detected by inductively coupled plasma mass spectrometry (ICP-MS) analysis. At 24 hrs postinjection, major organs were excised and extracted for ICP-MS analysis. **P<0.01.