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. 2019 Jul 30;38(17):e101064. doi: 10.15252/embj.2018101064

Figure 3. Peripheral immune challenge affects amyloid deposition in APP/PS1 mice.

Figure 3

  1. Representative cortical images of MXO4 staining for APP and APP/Nlrp3 −/− 15‐month‐old mice. Scale bar: 50 μm.
  2. Cortical amyloid plaque number and size quantification, and Amyloid‐beta1–40 and 1–42 ELISA quantification for APP and APP/Nlrp3 −/− mice (5‐ and 15‐month‐old) (mean of 8 ± SEM; two‐way ANOVA followed by Tukey's post hoc test, *P < 0.05, **P < 0.01, ***P < 0.001).